11,314 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Öcal M · 2025 · Scientific reports
Cold-wave disasters cause substantial loss of life and property, yet their global patterns remain poorly understood in a warming climate. Using EM-DAT records (1951-2023), we quantified cold-wave disaster frequency, mortality, and damages…
View details →Menpadi N, Chandra P, Dubey VK · 2025 · Journal of basic microbiology
We have earlier reported novel anti-leishmanial molecules, veratramine and hupehenine, targeting dephospho-coenzyme A kinase of the parasite. In our current investigation, we assessed the efficacy of these two steroidal alkaloids,…
View details →Dias VF, Albuquerque-Lima S, Navarro DMAF et al. · 2025 · Plant biology (Stuttgart, Germany)
Perfume flowers provide chemicals as a resource for specialized pollinators, that is, male euglossine bees. This system has been recorded in at least 15 families of Neotropical Angiosperms, including species of the bromeliad genus…
View details →Bi S, Wang C, Liu H et al. · 2026 · Frontiers in psychology
This study uses secondary analysis of a health survey dataset to explore the impact of completion time on the reliability and validity of online questionnaires. A total of 1,758 chronic low back pain patients recruited online were included…
View details →Yang Y, Xu L, Cao S et al. · 2026 · Industrial Crops & Products.
Accurate estimation of aboveground biomass (AGB) helps to monitor maize growth and yield prediction, and unmanned aerial vehicles (UAVs) have become one of the most significant technological tools in precision agriculture. However,…
View details →Durland M, Harsey SJ, Freyd JJ · 2026 · Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD)
DARVO (Deny, Attack, Reverse Victim and Offender) is a common tactic used by perpetrators of interpersonal violence to deflect blame and responsibility. Individuals' exposure to perpetrator DARVO has previously been measured using the…
View details →Bayır BRH, Ulutaş C, Nazlı E et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Introduction Headache is one of the most common neurological complaints in children and adolescents. Headache especially migraine in childhood significantly impacts daily life activities, including academic performance, and social…
View details →Manrique H, Castro-Llanos F, van Rompaey A et al. · 2025 · Applied Geography
Coca cultivation is expanding rapidly into the Amazon biome, raising concerns about its role in deforestation. While this relationship is well-studied in Colombia, Peru remains understudied in spatial modeling analyses. This study…
View details →Pirritano M, Buescher J, Staubach P et al. · 2026 · Communications biology
Discrimination of self from non-self RNA is a critical requirement for any cell to respond to infections and to maintain cellular integrity. We report novel functions for two RNA-dependent RNA polymerases (RDRs) in Paramecium. In…
View details →Spicher J, Wood ZJ, John-Henderson NA · 2026 · Journal of health psychology
Historical trauma and ongoing systemic inequities contribute to elevated levels of anxiety and problematic alcohol use among American Indians. The current study examines the relationship between recent trauma and problematic alcohol use,…
View details →Wingert AC, Connolly EJ · 2026 · Child abuse & neglect
Background Early life adversities (ELAs) are positively associated with violent victimization in early adulthood. The use of maladaptive coping behaviors, such as alcohol use, may exacerbate risk for victimization during this life course…
View details →Guillermier L, Sabourdy C, Four E et al. · 2026 · Epilepsy & behavior : E&B
Epilepsy is a neurological condition that can interfere with driving abilities through seizures and cognitive impairments. While legal frameworks often regulate driving eligibility, little is known about how people with epilepsy perceive…
View details →Paul RL, Porter DC, Mutschler-Aldine S et al. · 2026 · Environmental entomology
Evaluation of potential classical biological control agents typically begins with laboratory testing for their fundamental host range. These experiments are intended to evaluate the propensity for nontarget attack but often do so in highly…
View details →Weissflog A, Cinoğlu D, Dent DH et al. · 2025 · Biotropica.
Fungal pathogens affect seedling performance and mediate plant species coexistence in mature tropical forests. Yet the role of pathogens in driving tropical forest community dynamics during secondary succession has received little…
View details →Jiang H, Gao Y, Chen G · 2025 · Clim Dyn
Kilometer-scale modeling has identified a significant underestimation of nocturnal precipitation during summer in the southeast Tibetan Plateau (SETP), remaining a challenge that needs to be solved urgently. This study investigates the…
View details →Rodrigues AB, Abbad EL, Colmenares PA et al. · 2025 · Biotropica.
Understanding the ecological drivers of species diversity across spatial scales is essential for biodiversity conservation, particularly in highly complex ecosystems such as the Amazon. In this study, we investigate the influence of…
View details →Qin Y, Zhang P, Zhu Y et al. · 2025 · Agriculture, Ecosystems and Environment.
Few studies have comprehensively assessed the forage nutrition quality and pools among different plant functional groups across various grassland types and management practices. Moreover, the relationship between forage yield and nutrition…
View details →Häring M, Zhang Y, Zhang N et al. · 2026 · Biophysical journal
Cell junction remodeling is central to epithelial morphogenesis and tissue rheology and depends on the interplay between adhesion molecules and the actomyosin cortex. E-cadherin constitutes the molecular basis for epithelial cell adhesion,…
View details →Manzke L, O'Sullivan K, Tiefenbeck V · 2025 · Appetite
Food choices profoundly impact population health and the environment. Related research often relies on self-reported data, which is prone to biases, compromising the accuracy and validity of conclusions about consumer behavior. There are…
View details →Dantas TAV, Dantas A, Ganade G et al. · 2025 · Oecologia
Plant biodiversity can influence the structure of other trophic levels, with cascading effects on ecosystem functioning. Biodiversity-ecosystem function (BEF) experiments that manipulate tree diversity provide information on the mechanisms…
View details →Palacios-Lagunas DA, Hernández-Mondragón JC, Fuxe K et al. · 2026 · Pharmacology, biochemistry, and behavior
The promotion of prosocial behavior is a remarkable MDMA property. Such an effect is rather uncommon among other psychoactive substances and has been proposed to be of relevance for the potential therapeutic utility of MDMA. We aim to…
View details →Prochazkova L, Marschall J, Lippelt DP et al. · 2026 · Neuropharmacology
Objective Microdosing psychedelics has been widely reported to enhance focus and problem-solving, sparking interest in its potential to treat attentional disorders such as ADHD. However, existing studies largely rely on anecdotal evidence…
View details →Watts SH, Barsoum N, Park KJ et al. · 2025 · Restoration Ecology
INTRODUCTION: Mountain woodland restoration can enhance upland biodiversity and contribute to nature‐based solutions mitigating climate change impacts. However, high‐altitude planting of trees and shrubs requires considerable commitment of…
View details →Zubareva VM, Galkina KV, Lapashina AS et al. · 2026 · Archives of biochemistry and biophysics
ADP inhibition of ATP hydrolysis is a conserved regulatory mechanism found in virtually all F-type ATP synthases. It occurs when ADP binds tightly to a catalytic site in the absence of phosphate, locking the enzyme in an inactive…
View details →Caley A, Marzinelli EM, Mayer-Pinto M · 2025 · Marine environmental research
Multiple stressors such as Artificial Light at Night (ALAN) and warming are increasingly common in marine systems and can interact in complex ways. Microbial communities play critical roles in the functioning of coastal habitat-forming…
View details →Meng B, Hallmark AJ, Ohlert TJ et al. · 2025 · Ecology
Reordering of abundances among species is a common response in communities whether affected by anthropogenic drivers or natural disturbance. However, understanding how competitive relationships drive community dynamics under global…
View details →Schnücker GN, Salge J, Onnasch L · 2025 · Applied ergonomics
This study investigates the impact of Driver Advisory Systems (DAS) for eco-efficient driving on train drivers' job characteristics and job satisfaction, and their effects on acceptance and compliance with the system. Driving and…
View details →Ziermans T, Kok B, van Rijn S · 2025 · Journal of autism and developmental disorders
Purpose Attenuated positive symptoms constitute the most validated vulnerability marker for psychosis in non-autistic young adults. Early deviations in executive functioning and social cognition are believed to contribute to the onset of…
View details →Wilde ZC, Smith SD, Murphy MB et al. · 2026 · Journal of child & adolescent trauma
Adverse childhood experiences (ACEs) place adolescents at higher risk of developing physical and mental health problems later in life. Further, vulnerable adolescents-those from resource-limited households, communities, or schools; exposed…
View details →Koken G, Ertoy Karagol HI, Terece SP et al. · 2026 · International archives of allergy and immunology
Introduction Studies specifically focusing on drug-induced anaphylaxis (DIA) in children are few. There is no study comparing inpatient (IP) and outpatient (OP) settings in DIA, either in children or in adults. We aimed to compare the…
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