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11,314 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Testosterone treatment and respiratory medications and exacerbations in people prescribed inhaled corticosteroids: a nationwide cohort study.

Hansen ESH, Håkansson KEJ, Brustad N et al. · 2026 · Respiratory medicine

Background After puberty asthma is more common and often more severe in females, indicating a potential role of sex steroids. Observational and genetic studies suggest that higher testosterone levels are associated with improved lung…

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Negative / Null Result ReportMedicine

Variation in Management of Children With Coccidioidomycosis.

Michienzie C, Galgiani J, Fitzwater SP · 2026 · Pediatrics

Objective Coccidioidomycosis (CM) is not as well described in children as it is in adults. The Kaiser Permanente Southern California (KPSC) system provides care within an endemic region for CM, affording the opportunity to describe the…

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Negative / Null Result ReportMedicine

Evaluating the indirect interaction between glucagon-like peptide-1 receptor agonists and warfarin using real-world data.

Gilbert SJ, Vazquez SR, Gouripeddi R et al. · 2026 · Journal of thrombosis and thrombolysis

Increasing use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) raises concern for interactions with warfarin. Although GLP-1 RAs do not affect warfarin pharmacokinetics, their appetite-reducing effects may decrease vitamin K…

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Negative / Null Result ReportMedicine

The effect of a cardiac rehabilitation program including moderate-intensity continuous exercise training and high-intensity interval exercise training on sarcopenia and myokines in patients with heart failure.

Sönmez M, Alemdaroğlu E, Ata AM et al. · 2026 · Acta cardiologica

Background Cardiac rehabilitation (CR) has been shown to be beneficial in preventing and treating sarcopenia in those with cardiovascular disease. The aim of the study is to compare the effects of high intensity intermittent aerobic…

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Negative / Null Result ReportMedicine

Post-AI uterine lavage and PRP infusion reduce some uterine inflammation parameters but do not improve fertility in jennies inseminated with frozen semen.

Sancler-Silva YFR, Albino MV, Freitas MS et al. · 2026 · Journal of equine veterinary science

Background The use of cryopreserved semen in donkey jennies induces an exacerbated post-insemination uterine inflammatory response, resulting in low fertility rates. Aims/objectives This study aimed to investigate the effects of different…

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Negative / Null Result ReportMedicine

Crystalline Lens Shape During Accommodation in Children.

Pradhan A, Hughes RPJ, Woodman-Pieterse EC et al. · 2026 · Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)

Purpose To determine how accommodation affects lens shape in myopic and non-myopic children. Methods Participants included 76 non-myopic (spherical equivalent refraction (SER): 0.00 to +1.75 D) and 18 myopic children (SER = -3.50 to -0.75…

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Negative / Null Result ReportOpen accessMedicine

Postoperative Reduction in Postvoid Residual Urine Volume May Be Associated With Bladder Capacity Decrease Rather Than an Increase in Tidal Voided Urine Volume in Patients With Pelvic Organ Prolapse.

Kuroda K, Miyoshi H, Hamamoto K et al. · 2026 · The journal of obstetrics and gynaecology research

Aim More than half of patients with pelvic organ prolapse (POP) complain of lower urinary tract symptoms (LUTS), especially voiding difficulty. Surgical approaches such as laparoscopic sacrocolpopexy (LSC) and transvaginal mesh surgery…

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Negative / Null Result ReportMedicine

A wound dressing with copper and silver nanoparticles versus ionic silver hydrofibre dressing for the treatment of diabetic foot ulcers: a randomised clinical trial.

Roosimaa M, Ilumets H, Kaha T et al. · 2026 · Journal of wound care

Objective The objective of this trial was to compare the clinical performance and safety of a novel wound dressing containing silver and copper nanoparticles (Nanordica; Nanordica Medical OÜ, Estonia) (Ag/Cu) with the ionic silver-based…

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Negative / Null Result ReportMedicine

Loss of type III collagen has limited effect on tendon healing in young adult mice.

Tamburro MK, Carlson JA, Yen WK et al. · 2026 · Matrix biology : journal of the International Society for Matrix Biology

Tendon injuries account for considerable and escalating clinical burden. After injury, tendons heal poorly with persistent fibrovascular scar. Unlike healthy tendon which is type I collagen (COL1)-rich and highly-aligned, fibrovascular…

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Negative / Null Result ReportMedicine

Bacterial dysbiosis, cervicovaginal human papillomaviruses and inflammation persist in women living with HIV-1 after a year of antiretroviral treatment.

Lisco A, Borgognone A, Vanpouille C et al. · 2026 · The Journal of infectious diseases

Background The cervicovaginal microbiome may affect HIV-1 susceptibility and can in turn influence the prevalence and clinical course of HIV-1 and other sexually transmitted diseases. As the determinants, immunological correlates and…

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Negative / Null Result ReportMedicine

Low-frequency transient-evoked otoacoustic emission characteristics as potential indicators of hearing improvement in acute Ménière's disease: an exploratory analysis.

Yin TK, Sengar N, Fang TY et al. · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

PURPOSE: Fluctuating hearing loss in Ménière’s disease (MD) presents a key clinical challenge due to lack of reliable prognostic markers. The clinical value of transient-evoked otoacoustic emissions (TEOAEs) low-frequency components…

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Negative / Null Result ReportMedicine

Congestive heart failure in patients with acute respiratory distress syndrome: a secondary analysis of large randomized controlled trials.

Gkirgkiris K, Charalampaki E, Margioula E et al. · 2026 · Anaesthesia, critical care & pain medicine

Background stive heart failure may coexist and aggravate the non-cardiogenic pulmonary edema of acute respiratory distress syndrome (ARDS). Yet, patients with congestive heart failure are likely under-represented in ARDS trials. We aimed…

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Negative / Null Result ReportMedicine

Generating structure in soft solids: heat stable milk chocolate

Holian JA, Bolton MD, Wilson DI · 2025 · Current Research in Food Science

Addition of small amounts of glycerol to milk chocolate during the tempering stage can yield a product which exhibits enhanced mechanical strength and retards motion of the continuous phase (cocoa butter, a mixture of fats) of this dense…

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Negative / Null Result ReportMedicine

A Video Analysis Study Examining Neuromuscular Training Warm-Up Practices in Youth Soccer.

Lutz D, van den Berg C, Neill MG et al. · 2026 · Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine

Objectives To investigate time spent completing neuromuscular training (NMT) exercises in youth soccer team warm-up across a season considering sex, level of play, session type, and coach exposure and awareness of NMT. Design…

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Negative / Null Result ReportMedicine

Effect of Vitamin B12 Supplementation on Hematological and Athropometric Parameters in Children With Severe Acute Malnutrition, Aged 1 to 60 Months in Nutritional Rehabilitation Center (RCT).

Pathak BK, Maurya M, Mishra N et al. · 2026 · Clinical pediatrics

Microcytic hypochromic anemia is common in severe acute malnutrition (SAM) children, but macrocytic anemia (vitamin B12/folate deficiency) is not uncommon. Vitamin B12 deficiency leads to anemia and developmental slowing. We looked for the…

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