11,416 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Pietersen LC, Broekman N, Broekman N et al. · 2025 · Clinical transplantation
Acute kidney injury (AKI) is a common complication following liver transplantation (LT), with multifactorial etiology. It is believed that perioperative hemodynamic instability could lead to AKI. A temporary portocaval shunt (TPCS) could…
View details →Drost M, Fuhrmann G · 2026 · ACS infectious diseases
Pseudomonas aeruginosa is a notorious bacterial pathogen causing chronic pulmonary infections in people with cystic fibrosis (CF) due to its high tolerance to antibiotics and ability to form recalcitrant biofilms. A newer approach to…
View details →Kwieciński M, Kwiatkowski B, Ziomek W et al. · 2026 · Molecular biology reports
Despite major advances in medicine, cancer treatment remains a considerable challenge. The rising incidence of new cases and the frequent resistance to cytostatics suggest that standard therapies may be insufficient. This highlights the…
View details →Harcęko-Zielińska E, Górska A, Romantowski J et al. · 2025 · Journal of asthma and allergy
Background The influence of intestinal microorganisms on the development and course of allergic diseases has recently been the subject of intensive research, but studies describing changes in the intestinal microbiome of asthma patients in…
View details →Toraño P, Balmaseda A, Bordons A et al. · 2025 · Food microbiology
Oenococcus oeni is the main species of lactic acid bacteria (LAB) responsible for malolactic fermentation (MLF) in winemaking. MLF development can present difficulties because of the harsh, stressful conditions of wine. Yeast mannoproteins…
View details →Roberts E, Francesconi M, Flouri E · 2025 · Stress (Amsterdam, Netherlands)
Prenatal stress has been associated with poor cognitive outcomes in offspring, but the evidence about the role of exact timing of exposure is mixed and that about causal mechanisms is limited. Using the Avon Longitudinal Study of Parents…
View details →Pec J, Nigl M, Fox H et al. · 2026 · Journal of cardiovascular development and disease
(1) Background: Early treatment of sleep-disordered breathing (SDB) with adaptive servo-ventilation (ASV) after acute myocardial infarction (AMI) has been shown to improve myocardial salvage. This analysis evaluates nocturnal…
View details →Hansen EK, Hansen D, Schalkwijk C et al. · 2026 · Blood purification
Introduction Far infrared radiation may improve arteriovenous fistula maturation and patency rates in patients on hemodialysis (HD). The mechanism is proposed to involve anti-inflammatory and vasodilatory effects in the arteriovenous…
View details →Siffredi V, Liverani MC, Fernandez NB et al. · 2025 · Child: care, health and development
Background Very preterm (VPT) adolescents show executive and socio-emotional difficulties that persist into adulthood. Beneficial effect of mindfulness-based intervention (MBI) has been found in VPT young adolescents immediately after the…
View details →Weeks JJ, Johnson PA, Garcia-Tomas V · 2025 · Current opinion in anaesthesiology
Purpose of the review Regional anesthesia is valuable in peripheral vascular surgery, either as the primary anesthetic or as an adjuvant to general anesthesia. Patients presenting for vascular surgery often have associated comorbidities…
View details →Barone M, Guli L, Centurión J et al. · 2026 · Cranio : the journal of craniomandibular practice
Objective To compare the effects of two transcutaneous electrical stimulation (TES) patterns applied to the auricular branches of the auriculotemporal nerve on nociceptive processing. Methods Twelve asymptomatic volunteers received…
View details →Cieślewicz M, Szczepanek-Parulska E, Witowska A et al. · 2026 · Journal of endocrinological investigation
Purpose Our study aimed to evaluate the performance and concordance of parathyroid hormone wash-out (PTHw) and 99m Tc-MIBI+SPECT/CT (MIBI) in preoperative localization for patients with primary hyperparathyroidism (PHPT), and assess…
View details →Zwierzewicz Z, Szpakowska A, Bistroń D et al. · 2025 · Archiwum medycyny sadowej i kryminologii
The aim of the study The aim of the study was to accurately determine the incidence of white autopsies and to identify possible conditions responsible for such autopsies by means of analyzing confirmed causes of death in the same age…
View details →Dones AM, Bou Ghanem G, Kessler C et al. · 2026 · Retina (Philadelphia, Pa.)
Purpose We performed a retrospective cross-sectional study to determine whether there is a significant difference in the percentage of patients with diagnosed inherited macular or peripheral disease who receive more definitive genetic…
View details →Aggarwal P, Singh H, Kumar R et al. · 2026 · European journal of nuclear medicine and molecular imaging
Purpose Fever of unknown origin (FUO) is a prolonged fever with unknown etiology after an extensive outpatient or inpatient workup. 18 F-Flurodeoxyglucose (FDG) positron emission tomography (PET) with computed tomography (CT) has shown a…
View details →Nguyen CD, Panganiban HP, Karahalios A et al. · 2026 · Critical care medicine
Objectives Enteral magnesium replacement may be as effective as IV replacement while being a cheaper and more environmentally sustainable intervention. The primary objective was to evaluate whether enteral magnesium is noninferior to IV…
View details →Liao G, Zhang S, Wei Y et al. · 2026 · BMC medical informatics and decision making
Background The standard HIV diagnostic algorithm comprises sequential serological screening, confirmatory antibody testing, and nucleic acid confirmation when necessary. This multi-step process often causes diagnostic delays, particularly…
View details →Shiba Y, Aoki K, Ohka F et al. · 2025 · AJNR. American journal of neuroradiology
Background and purpose Differentiating between a brain tumor and a nontumorous lesion remains a diagnostic challenge, particularly when conventional imaging modalities such as CT and MRI provide inconclusive results. While 11 C-methionine…
View details →Kumar R, Gravett S, Jelic V et al. · 2026 · Neurology
Background and objectives The α-synuclein (α-syn) seed amplification assay (SAA) has shown promising results for diagnosing dementia with Lewy bodies (DLB) using CSF samples. A barrier to implementing α-syn SAA clinically is the use of…
View details →Tornvall S, Blomberg L, Hirschberg AL · 2025 · Psychoneuroendocrinology
The objective of this study was to investigate the association of menstrual cycle phases on sexual function, well-being, and mood in young healthy women. Previous research has shown inconclusive results likely due to using non-validated…
View details →Wilcox A, Hall M, Menzies J et al. · 2025 · Science of the Total Environment
The biodegradability of water-soluble carboxymethyl cellulose (CMC) polymer, degree of substitution of 0.65, was evaluated in screening and simulation assays using activated sludge as the inoculum. In an OECD 301B, CMC 0.65 was slowly…
View details →Abdulrasak M, Axler O, Kapás B et al. · 2026 · Diagnostics (Basel, Switzerland)
Protein-losing enteropathy (PLE) is an uncommon and often underrecognized manifestation of lymphoproliferative disorders and may be difficult to diagnose when conventional gastrointestinal investigations are unrevealing. We present an…
View details →Racano E, Spinelli C, Sacco G et al. · 2026 · Scientific reports
Early detection and documentation of anterior segment opacities in infants (aged 1–6 months) is limited by resource constraints and specialist availability. This study aimed to evaluate the usefulness of digital infrared reflex testing…
View details →Shah KV, Jung C, Talian D et al. · 2025 · OTO open
Objective While the etiology of Meniere's disease (MD) is likely multifactorial, genetics are thought to play a role. Several previous studies have yielded inconclusive results, potentially due to phenotypic uncertainty and variable…
View details →Nguyen MD, Park D, Scott JW et al. · 2026 · Science advances
Landau predicted that transverse sound propagates in a Fermi liquid with sufficiently strong interactions such as for liquid 3 He, unlike a classical fluid that cannot support shear oscillations. Previous attempts to observe this unique…
View details →Gay A, Laudet F, Meynard P et al. · 2026 · Orthopaedics & traumatology, surgery & research : OTSR
Introduction Infection is a significant and challenging complication of total hip and knee arthroplasties. Diagnosing chronic periprosthetic joint infection (PJI) can be difficult, particularly when joint aspiration yields inconclusive…
View details →Payton C, Kvaratskhelia N, Chalfin M et al. · 2025 · Journal of immigrant and minority health
Cancer screening can detect cancer at an early stage and decrease cancer morbidity and mortality. Refugee populations may have had limited access to cancer screening before arrival in the United States. A cross-sectional analysis of…
View details →Kaseb A, Benider H, Treglia G et al. · 2025 · European journal of clinical investigation
Background 4D-CT has garnered attention as complementary imaging for patients with primary hyperparathyroidism (pHPT). Herein we evaluated a diagnostic strategy using [ 18 F]Fluorocholine Positron Emission Tomography/Computed Tomography…
View details →Kuyucu M, Erdogan KM, Adiyaman D et al. · 2025 · Medicine
This study shares our 5-year experience with chorionic villus sampling (CVS) and analyzes the indications, results, and complications of this procedure. We conducted a retrospective analysis of data from singleton pregnancies that…
View details →de Oliveira Castro Marques TR, Vidal SA, da Costa HA et al. · 2026 · Hematology, transfusion and cell therapy
Background Stroke, the most severe neurological complication of sickle cell disease, can result in irreversible sequelae and death. Transcranial Doppler combined with periodic blood transfusions reduces the chances of stroke by 90 %. In…
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