11,416 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Abassi W, Ouerghi N, Feki O et al. · 2026 · Clinics (Sao Paulo, Brazil)
Objective Obesity is a major independent risk factor for chronic kidney disease. High-Intensity Interval Training (HIIT) is recognized as an interesting therapeutic strategy in managing obesity and related disorders. However, there is…
View details →Oğuz F, Türk SK, Yavan MA · 2026 · Scientific reports
This controlled retrospective study aimed to evaluate the effects of maxillary protraction therapy on mandibular symphysis morphology. In this regard, 35 growing individuals with skeletal class III malocclusion due to maxillary…
View details →Dantsi F, Kypraiou A, Kouvelas N et al. · 2026 · Sports (Basel, Switzerland)
Most detraining research in swimming has focused on competitive athletes, whereas less is known about recreational university swimmers, a population commonly exposed to temporary interruptions in structured training. This study examined…
View details →Schuckit MA, Smith TL, Danko G et al. · 2026 · Alcohol, clinical & experimental research
Objectives The retrospective self-report of the effects of alcohol (SRE) questionnaire generates three scores reflecting drinking quantities required for effects: SRE-5 (first five times of drinking), SRE-3 (recent 3 months of drinking),…
View details →Jambor T, Goc Z, Tokarova K et al. · 2025 · Physiological research
The growing popularity of microgreens is due to several health-promoting effects. Current evidence suggests a reduction in the risk of cardiovascular and neurodegenerative diseases, or anti-carcinogenic and anti-inflammatory effects.…
View details →Puls HT, Lindberg DM, Noelke C et al. · 2026 · Academic pediatrics
Objective To determine whether community advantage moderated rates of hospital encounters for child physical abuse during the COVID-19 pandemic. Methods This was a population-based retrospective study of 12 states during 2019 to 2021. The…
View details →Fuchs S, Majer M, Ma Y et al. · 2026 · Pflugers Archiv : European journal of physiology
Diabetic nephropathy (DN) is characterized by a decline in renal function resulting from hyperglycaemia and is often requiring dialysis or renal transplantation. Yet, the signalling events causing DN and the effective treatment options are…
View details →Noell SE, Colville EC, Marshall A et al. · 2026 · FEMS microbiology ecology
The Bratina Island meltwater ponds (McMurdo Ice Shelf, Antarctica) host complex microbial communities in the form of benthic microbial mats. These ponds are long-lasting but can experience significant alterations in physicochemistry on an…
View details →Jahanian Najafabadi A, Rastegari A, Imani H et al. · 2026 · Acta psychologica
The plasticity of body representation in response to tool use is a dynamic process that evolves across the lifespan. Research has shown that tools can become integrated into the body representation, effectively being treated as extensions…
View details →Bicici Ulusahin S, Celik C, Abut CZ et al. · 2026 · Health care for women international
Primary dysmenorrhea (PD) is a prevalent condition in young women, characterized by menstrual pain, sleep disturbances, and reduced physical activity. Yoga has been suggested as a non-pharmacological intervention. We examined the effects…
View details →Kim J, Han E · 2026 · Disability and health journal
Background Households including a member with disabilities carry greater caregiving burdens than those without, increasing the likelihood of economic and emotional imbalances. Objectives Using Korea Welfare Panel Study (KOWEPS) waves 1-19,…
View details →Blasco-Giner C, Salanova M, Meneghel I · 2026 · The Journal of general psychology
This study draws on the Conservation of Resources Theory to examine two objectives: (1) whether consideration of future consequences (CFC) moderates the relationship between psychological capital (PsyCap) and innovative work behavior…
View details →Jurgelewicz M, D'Adamo CR, Malaya CA · 2026 · Integrative medicine (Encinitas, Calif.)
Background Geranylgeraniol (GG) is a naturally occurring isoprenoid that is involved in steroid hormone synthesis, the endogenous production of coenzyme Q10 (CoQ10), healthy muscle function, bone metabolism, and cellular energy production.…
View details →Te Lindert L, van Meijeren-Pont W, Meesters J et al. · 2026 · Disability and rehabilitation
Purpose Reducing sedentary behaviour (SB) in stroke rehabilitation is essential, yet effects of most interventions remain limited. This review used the Behaviour Change Wheel to identify: (1) barriers and facilitators for reducing SB of…
View details →Cheng C, Li M, Sun B et al. · 2026 · Plant science : an international journal of experimental plant biology
Rho-like GTPases of plants (ROPs) regulate diverse cellular processes, but their roles in tomato drought responses are largely unknown. In this study, nine ROP genes were identified in tomato (Solanum lycopersicum). Among them, SlROP4, the…
View details →Besora-Moreno M, Jiménez-Ten Hoevel C, Queral J et al. · 2026 · Journal of cachexia, sarcopenia and muscle
Background Management of sarcopenia by nutritional and lifestyle interventions is a challenge. The aim is to assess the effectiveness of a phenolic-rich extra virgin olive oil (EVOO), alone or combined with a prebiotic (PREB)…
View details →Zhu H, Shipman J, Ouyang W et al. · 2026 · NPJ advanced manufacturing
Recombinant monoclonal antibody (mAb) therapeutics exhibit lot-to-lot glycosylation variation influenced by manufacturing processes, which remains underexplored publicly. This study analyzed five years of trastuzumab and adalimumab lots,…
View details →Yao PY, Hendrix JM · 2026
The concept of a regional anesthesia technique that provides neural blockade of the entire lumbar plexus, a lumbar plexus block, dates back nearly 50 years. The first description of such a block by Winnie et al in 1973 was an “inguinal…
View details →Biguino B, Haigh ID, Dias JM et al. · 2025 · Scientific reports
Marine Heat Waves (MHWs) have been the focus of numerous studies due to the dramatic consequences they can have on coastal systems. However, Marine Cold Spells (MCSs) can also have harmful effects on the environment while play an important…
View details →Cesna S, Bielinis A, Zvirblis T et al. · 2026 · Cardiology in the young
Objectives Despite the effectiveness of the surgical or percutaneous treatment of coarctation of the aorta, the presence of hypertension in these patients remains a common and concerning issue. This study was undertaken to explore the…
View details →Andrés AI, Martín-Mateos MJ, D'Arrigo M et al. · 2026 · Food chemistry
This study evaluated the effects of high hydrostatic pressure (HHP)-treated white (WGP) and red grape pomace (RGP) on oxidative stability, volatile compounds, and polycyclic aromatic hydrocarbons (PAHs) in barbecued Frankfurter sausages.…
View details →Kit-Anan W, Vaewpanich J, Anantasit N · 2026 · Children (Basel, Switzerland)
Background: Extubation failure increases morbidity and mortality. Non-invasive ventilation (NIV), including high-flow nasal cannula (HFNC), can reduce reintubation rates. Current practice often involves prophylactic use of NIV…
View details →Teh WT, Chung J, Donoghue JF et al. · 2026 · Human reproduction (Oxford, England)
Study question Does endometrial gene expression change across consecutive cycles and after endometrial injury? Summary answer Although paired endometrial samples collected from the same woman across two consecutive cycles show greater…
View details →Jafari A, Amani Beni S · 2026 · Maturitas
Background Myonectin is a myokine that regulates lipid metabolism, and levels are often reduced in obesity and insulin resistance. This study examined whether the timing of exercise influences myonectin and metabolic responses to…
View details →Başaran R, Demirci H, Başaran TÖ et al. · 2026 · BMC geriatrics
Ramadan fasting involves prolonged daytime abstinence from food and fluid intake and may influence cardiovascular and physiological regulation. Although prior studies have examined metabolic and cardiovascular effects, evidence on…
View details →Delling C, Kirchner M, May K et al. · 2026 · Parasites & vectors
Background Cryptosporidium parvum and Giardia duodenalis (assemblages A and B) are ubiquitously occurring protozoan parasites infecting a broad range of hosts. Co-infection with both parasites in suitable hosts have been reported, but…
View details →Flores-Bello C, Correa-Muñoz E, Sánchez-Rodríguez MA et al. · 2026 · Healthcare (Basel, Switzerland)
Background/Objectives : Tai Chi (TC) practice has been shown to positively affect the physical, psychological, and cognitive health of older adults. However, discrepancies persist regarding its effectiveness compared to strength training…
View details →Hooper P, Jin J, O'Brien K et al. · 2026 · Magnetic resonance in medicine
Purpose To measure magnetic susceptibility (χ) with Quantitative Susceptibility Mapping (QSM) and evaluate its repeatability using four phantom doping materials relevant to QSM applications. Methods A cylindrical phantom was constructed…
View details →Konieczna M, Puz P, Gałuszewski M et al. · 2026 · Journal of clinical medicine
Background: The neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) reflect the balance between innate and adaptive immunity and may indicate systemic inflammation. Objectives: To evaluate longitudinal changes in…
View details →Botía M, Cerón JJ, Martínez-Subiela S et al. · 2026 · Veterinary and animal science
Non-invasive biomarkers are essential for assessing stress and welfare. Saliva is a suitable sample type because it can reflect endocrine, immune, inflammatory and redox responses without causing stress from handling. This study examined…
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