11,314 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Ugur MA, Okut G, Buyuktoka RE et al. · 2026 · BMC geriatrics
Background Emergency laparotomy in older adults is associated with substantial morbidity and mortality, necessitating accurate and rapid preoperative risk stratification. Established risk models such as National Emergency Laparotomy Audit…
View details →Lee J, DeGroot W · 2026 · Journal of the American Veterinary Medical Association
Objective To assess whether thoracic radiographs in dogs with gastric dilatation-volvulus (GDV) are associated with the decision to proceed with surgery and survival to discharge. Methods A retrospective cohort study of dogs with GDV…
View details →Lewis J, Liu AM, Johnson C et al. · 2026 · Injury
Background Trauma volume can vary significantly throughout the year. Identifying factors associated with trauma volume variation can be helpful in allocating resources and staff during busy trauma periods. The present study aimed to…
View details →Gunderson AK, Kwon T, Kumarasinghe Y et al. · 2026 · Transactions of the Royal Society of Tropical Medicine and Hygiene
Background Beliefs of a child's primary caregiver are known to influence immunization uptake. As coverage increases, the characteristics of households with undervaccinated children may be shifting. Methods We conducted a cross-sectional…
View details →Gaertner LHC, Reininger KM, Briken P · 2026 · Journal of sex research
Mentalizing ability - the capacity to understand behavior as motivated by intentional mental states - develops within attachment relationships and has recently been suggested to influence sexual health. This study examined whether…
View details →Piran CMG, Cargnin AVE, Mori MM et al. · 2026 · Revista brasileira de enfermagem
Objectives to analyze factors associated with poor adherence and loss to follow-up among adolescents and young people living with HIV. Methods ambidirectional cohort study of 512 adolescents and young people with HIV receiving treatment at…
View details →Gul F, Ullah A, Li Y et al. · 2026 · BMC endocrine disorders
Obesity, especially visceral obesity, is a major health issue globally, leading to metabolic disorders. Visceral fat accumulation is closely linked to insulin resistance and metabolic abnormalities. The role of branched-chain amino acids…
View details →Sriram N, Muller R, Jain R et al. · 2026 · Clinical neurology and neurosurgery
Objective Surgical decompression is often needed to relieve symptoms and prevent long-term disability from compressive peripheral nerve pathologies. This study applied the Social Vulnerability Index (SVI) to characterize utilization…
View details →Kowra S, Singh H, Singh V et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Introduction Estrogens are crucial in the development and growth of skeletal systems. Estrogen receptor alpha (ESRα) and beta (ESRβ) are crucial regulators of estrogen response. Estrogen receptor genes (ESR1 and ESR2) have been extensively…
View details →Koçyiğit YB, Karaoğlan B, Kuruoğlu A · 2026 · Scientific reports
We examined whether metacognitive beliefs were associated with fibromyalgia impact and compared metacognitive beliefs between patients with Fibromyalgia Syndrome (FMS) and matched healthy controls. We hypothesized that Metacognitions…
View details →Acar Ozer T, Arslan M, Şahin K · 2026 · Nutrition and health
BackgroundMetabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is one of the most prevalent chronic liver diseases worldwide and is strongly associated with metabolic dysfunction. Dietary patterns such as the Mediterranean and…
View details →Tophkhane C, Yang S, Zhao ZJ et al. · 2026 · International journal of oncology
Subsequently to the publication of the above article, an interested reader drew to the authors' attention that the control β‑actin blots shown for the western blots portrayed in Figs. 1B and 2B were strikingly similar after a slight…
View details →Oh MS, Park KY, Jeong HB et al. · 2026 · BMC neurology
Background We aimed to determine cut-off values of factors affecting early neurological improvement in patients after recombinant tissue plasminogen activator therapy for acute ischemic stroke. Methods A total of 135 patients with acute…
View details →Moreira A, Azevedo R, Costa JA et al. · 2026 · European journal of dentistry
Objective Drug addiction is a growing global health concern with significant oral health consequences. Cannabis and cocaine are among the most frequently used illicit drugs, contributing to a high burden of oral pathologies. This study…
View details →Helvich J, Machu V, Novak L et al. · 2026 · Archives of public health = Archives belges de sante publique
Background Problematic social media use (PSMU) has become a critical public health concern. However, little is known about how the associations between PSMU, mental health, and substance use differ depending on participation in distinct…
View details →Borgehammar J, McClenahan B, Miller E et al. · 2026 · The Journal of manual & manipulative therapy
Objective Developing psychomotor competence in orthopedic manual physical therapy (OMPT) techniques is fundamental to post-professional physical therapy education. Concerns persist about whether online instructional models and the rise of…
View details →Vu NTH, Quach DT, Miyauchi S et al. · 2026 · Digestion
Introduction A family history of chronic constipation (CC) is considered an important predisposing factor for developing CC. This study aimed to compare the associations of maternal and paternal histories of CC with constipation in…
View details →Sharma S, Aschner A, Kabir N et al. · 2026 · The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
Rationale The ketogenic diet (KD) is a well-established therapeutic option for children with non-surgical drug-resistant epilepsy (DRE). The purpose of this study was to determine whether specific anti-seizure medications (ASM) are…
View details →Tall S, Pettersson J, Härkönen T et al. · 2026 · Diabetes care
Objective We assessed whether 1) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination is associated with the risk of type 1 diabetes and 2) SARS-CoV-2 vaccination or infection is associated with disease severity at type…
View details →Kobayashi T, Takahara M, Kikuchi S et al. · 2026 · European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
Objective A single segment great saphenous vein (GSV) with a diameter ≥ 3.0 mm is widely accepted as the standard conduit for tibial and pedal bypass in chronic limb threatening ischaemia (CLTI) based on studies in European and American…
View details →Keskimölö T, Kiviaho A, Karppinen J et al. · 2026 · Aerospace medicine and human performance
Introduction Fighter pilots are exposed to high +Gz forces, helmet-mounted equipment, and extreme head positions that potentially cause cervical spine degeneration and pain. This study aimed to investigate whether individual +Gz exposure,…
View details →Taymur BD, Toklucu G, Gunkaya OS et al. · 2026 · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
Objective To evaluate the association between Selenium (Se) and other micronutrients (iron, ferritin, copper, zinc, and vitamin B12) and the development of preeclampsia (PE), and to assess their predictive performance. Study design An…
View details →Szabóová S, Duraníková O, Örzsik B et al. · 2026 · Lipids in health and disease
Background Cardiometabolic factors may influence migraine biology through metabolic, inflammatory, and vascular mechanisms, but studies examining insulin resistance and dyslipidaemia in migraine have yielded inconsistent results, partly…
View details →Rivas-Nieto AC, Alver SK, Mooney SJ et al. · 2026 · Journal of physical activity & health
Background Physical activity (PA) may be a modifiable factor for chronic kidney disease (CKD) prevention, but evidence specific to Hispanic/Latino populations is limited. Our objective was to examine associations between PA type/volume…
View details →de Freitas JJA, Nardotto DDMP, Netto LC et al. · 2026 · Infection
Purpose Although advances in intensive care have improved survival of patients with severe leptospirosis, it remains with high mortality. We aimed to identify factors associated with in-hospital mortality among patients with severe…
View details →Demirci SC, Aşik UB, Menkü BE et al. · 2026 · BMC psychiatry
Background Symptoms of attention-deficit/hyperactivity disorder (ADHD) are commonly observed in individuals with substance use disorders (SUD) and may be associated with increased addiction severity. Time perspective is a potential…
View details →Gillikin AP, Rabinovich EP, Barajas-Gamboa JS et al. · 2026 · Surgical endoscopy
Background Post-discharge venous thromboembolism (VTE) chemoprophylaxis after metabolic and bariatric surgery is variably implemented in clinical practice, although the optimal pharmacologic agent and dosing regimen remain unclear. This…
View details →Montalva-Valenzuela F, Guzmán-Muñoz E, Castillo-Paredes A et al. · 2026 · Healthcare (Basel, Switzerland)
Background: The standing long jump (SLJ) is a field-based test of lower-limb muscular fitness in youth and a proposed indicator of health-related physical fitness. However, evidence on its relationship with psychological, sleep, dietary,…
View details →de Ruyter H, Aitokari L, Iqbal A et al. · 2026 · The Journal of pediatrics
Objective To investigate associations of perinatal and lifestyle factors with alanine aminotransferase (ALT) levels as an early indicator of metabolic dysfunction-associated steatotic liver disease (MASLD). Study design Data from the…
View details →Kim BI, Cheng R, Grabov E et al. · 2026 · The Journal of arthroplasty
Background Larger femoral heads have been proposed to reduce dislocation risk following total hip arthroplasty (THA). While the benefit of increasing head size from 28 or 32 mm to ≥ 36 mm is well established, it remains unclear whether…
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