e-ISSN: Pending
WASTE Journal

Browse the failure-mode index

11,416 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Evaluation of a structured type 1 diabetes education program for adolescents and parents: Teens Empowered to Actively Manage Type 1 (TEAM T1).

Hagger V, Hendrieckx C, Cotterill A et al. · 2026 · Diabetic medicine : a journal of the British Diabetic Association

Aim To examine changes in psychological and clinical outcomes among adolescents and parents after structured type 1 diabetes education delivered in routine care. Methods Teens Empowered to Actively Manage Type 1 Diabetes (TEAM T1) is a…

View details →
Negative / Null Result ReportMedicine

Prophylactic cavotricuspid isthmus ablation in addition to pulmonary vein isolation is associated with improved recurrence-free survival in patients aged > 70 years with paroxysmal atrial fibrillation.

Li JL, Wu JH, Zhao X et al. · 2026 · Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

BACKGROUND: The role of prophylactic cavotricuspid isthmus (CTI) ablation remains controversial in atrial fibrillation (AF) patients without atrial flutter (AFL). Given the strong association between AF, AFL, and age, this study aimed to…

View details →
Negative / Null Result ReportOpen accessMedicine

Effect of short-term supplemental oxygen therapy on 6-min walk distance in highlanders at risk for pulmonary hypertension: a randomised, crossover trial.

Hertig D, Furian M, Müller J et al. · 2026 · ERJ open research

Background Little is known about the effects of portable supplemental oxygen therapy (SOT) to improve exercise performance in highlanders at risk for high-altitude pulmonary hypertension (HAPH). We aimed to investigate whether SOT improves…

View details →
Negative / Null Result ReportMedicine

Effects of propionic acid inclusion and ensiling time on in situ ruminal starch degradability of high-moisture flint corn grain silage.

Martins BM, Vieira RAM, Bittencourt CS et al. · 2025 · Journal of dairy science

This study evaluated the effects of propionic acid inclusion (PAI; 0, 0.25, and 0.50% of fresh matter) and ensiling time (ENT; 30, 60, 90, 120, 150, and 180 d) on the chemical composition, fermentation profile, DM losses, and in situ…

View details →
Negative / Null Result ReportMedicine

Postoperative Radiotherapy May Improve Survival in Certain Patients with pN2 Non-Small Cell Lung Cancer Who Do Not Have Extranodal Extension.

Jeon SH, Song C, Jeon JH et al. · 2026 · Cancer research and treatment

Purpose The aim of this study was to identify subgroups of patients with pathologic N2 (pN2) non-small cell lung cancer (NSCLC) who may benefit from postoperative radiotherapy (PORT). Particular attention was given to evaluating whether…

View details →
Negative / Null Result ReportMedicine

Comparing Clinical and Radiological Outcomes for a Three-Dimensional Printed Highly-Porous Cup and a Hydroxyapatite-Coated Non-Highly-Porous Cup in Total Hip Arthroplasty Using Propensity Score Matching.

Okazaki T, Imagama T, Matsuki Y et al. · 2026 · The Journal of arthroplasty

Background The use of highly-porous acetabular components in total hip arthroplasty (THA) has gained popularity. To elucidate the clinical and radiological outcomes of three-dimensional (3D)-printing highly porous cups, we compared…

View details →
Negative / Null Result ReportMedicine

Hamstring-to-quadriceps ratio across menstrual cycle phases in physically active women: a repeated-measures study.

Heinrich C, Hofstaetter H, Puschkasch-Möck S et al. · 2026 · European journal of applied physiology

Objective To evaluate conventional hamstring-to-quadriceps ratio across the menstrual cycle in distinct angular velocities in an eumenorrheic, physically active population. Design Repeated measures within-subjects design. Methods…

View details →
Negative / Null Result ReportMedicine

Medium Cut-Off Versus High-Flux Dialyzers and Changes in Beck Depression Inventory Scores in Maintenance Hemodialysis: An Exploratory Observational Study.

Avsar FN, Erinc O, Sahutoglu T · 2026 · Hemodialysis international. International Symposium on Home Hemodialysis

Introduction Depression is prevalent in maintenance hemodialysis patients and is influenced by the interplay of physical and mental health. Rather than a direct antidepressant effect of dialyzer membrane type, improved clearance of middle…

View details →
Negative / Null Result ReportMedicine

Acute cholecystitis in the robotic era: comparative safety and feasibility of robotic and laparoscopic cholecystectomy in an acute care surgery service.

Pontecorvo AA, Cornejo J, Tsenteradze T et al. · 2026 · Journal of robotic surgery

This study aimed to evaluate and compare perioperative outcomes of robotic versus laparoscopic cholecystectomy in patients with acute cholecystitis within an Acute Care Surgery setting. A retrospective cohort study was conducted including…

View details →
Negative / Null Result ReportMedicine

Interaction model of client health behavior-based nursing intervention improves outcomes in patients with pressure injury: A quasi-experimental study.

Guan X, Li X, Yue M et al. · 2026 · Scientific reports

Pressure injury (PI) prevention requires sustained nursing behaviors from patients, caregivers, and nurses. This single-center quasi-experimental, non-randomized, non-equivalent control group study enrolled 60 inpatients with PI or high PI…

View details →
Negative / Null Result ReportMedicine

Child maltreatment recognition and reporting attitudes among pediatric nurses and physicians in Türkiye: A cross-sectional comparative study.

Çarikçi F, Girgin BA, Harmanci NF et al. · 2026 · Child abuse & neglect

Aim To examine and compare the proficiency of pediatric physicians and nurses in recognizing the signs of and risk factors for child maltreatment, as well as to determine the relationship between this proficiency and their reporting…

View details →
Negative / Null Result ReportMedicine

Safety and Efficacy of Oral Tacrolimus Induction Therapy in Elderly Patients with Ulcerative Colitis: A Subanalysis of a Large Multicenter Retrospective Cohort Study.

Inokuchi T, Hiraoka S, Oshima N et al. · 2026 · Gerontology

Introduction We previously reported the findings of a multicenter retrospective cohort study investigating the efficacy of oral tacrolimus induction therapy in patients with ulcerative colitis (UC). In this subanalysis, we specifically…

View details →
Negative / Null Result ReportMedicine

Reduced Left Atrial Reservoir Strain Is Associated with Histopathologically Confirmed Atrial Natriuretic Peptide-Amyloid Deposition.

Nishino S, Asada Y, Nishino C et al. · 2026 · Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

Background Isolated atrial amyloidosis is characterized by atrial natriuretic peptide- (ANP-) amyloid deposition confined to the atria and has been primarily linked to atrial fibrillation. However, its relationship with atrial mechanical…

View details →
Negative / Null Result ReportOpen accessMedicine

Enamel Microhardness of Resin-Infiltrated White Spot Lesions After Bleaching With and Without ACP: An In Vitro Study.

Hegde P, Acharya SR, Mayya A et al. · 2026 · International journal of dentistry

Background White spot lesions (WSLs) represent the earliest clinical manifestations of enamel demineralization. Resin infiltration (RI) is a minimally invasive method used to mask WSLs for esthetic improvement; however, infiltrated enamel…

View details →
Negative / Null Result ReportMedicine

Comparative Evaluation of Mealworm (Tenebrio molitor) Larvae as an Alternative Diet for the Mass Rearing of Nesidiocoris tenuis.

Lee J, Hwang HS, Li Y et al. · 2026 · Archives of insect biochemistry and physiology

Nesidiocoris tenuis is an important natural enemy widely used for the biological control of small pests in vegetable crop systems. Its successful implementation in commercial programs depends on reliable and cost-effective mass rearing,…

View details →
Negative / Null Result ReportOpen accessMedicine

Early Immune Alterations in Adult Patients with Trauma According to Injury Severity: Cell-Death Patterns and Inflammatory Mediator Profiles.

Park SJ, Kim JY, Yun S et al. · 2026 · Journal of clinical medicine

Background/Objectives : Trauma triggers complex early immune responses. However, the relationship among trauma severity, changes in immune cell survival, and circulating inflammatory mediators remains unclear. This study compared early…

View details →
Negative / Null Result ReportMedicine

Longitudinal Changes in Health Utility Scores During the Perioperative Period Among Patients With Oral Cancer: An Analysis of the Effect of Older Age and Social Background.

Sasaki M, Aoki T, Uchibori M et al. · 2026 · Oral diseases

Objective Many countries have implemented health technology assessment of their public medical insurance programs owing to rising social security costs from ageing populations and expensive emerging medical technologies. Clarifying factors…

View details →
Negative / Null Result ReportOpen accessMedicine

Effects of insect-derived protein form and replacement level on growth performance and skeletal traits in broiler pheasants (Phasianus colchicus).

Osiak-Wicha C, Kras K, Tomaszewska E et al. · 2026 · Poultry science

This study evaluated black soldier fly (Hermetia illucens) products as alternatives to soybean meal protein in broiler pheasants, focusing on growth performance and skeletal traits in both sexes. Birds were assigned to five dietary…

View details →
Negative / Null Result ReportMedicine

Comparison of Dexmedetomidine Administration Strategy for Propofol-Based Pediatric Sedation for Magnetic Resonance Imaging: A Retrospective Study.

Kim TW, Ji SH, Park JB et al. · 2026 · Paediatric anaesthesia

Background Intravenous dexmedetomidine is a safe and effective adjunct in propofol-based sedation. Dexmedetomidine is typically administered as a loading dose, followed by continuous infusion or not. Whether the addition of a maintenance…

View details →
Negative / Null Result ReportMedicine

Immune-impulsivity link: association between peripheral inflammatory ratios and borderline personality disorder.

Raj R, Nabi J, Gidwani S et al. · 2026 · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan

Objectives To determine associations between impulsivity and peripheral inflammatory ratios in patients with borderline personality disorder (BPD). Methods Consecutive patients aged ≥18 years with a diagnosis of BPD who presented to the…

View details →