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11,416 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Relationship Between Pulmonary Thromboembolism, its Mortality and Seasonal, Meteorological Factors

Seda Beyhan Sağmen, Sevda Cömert, Nesrin Kıral et al. · 2019 · Southern Clinics of Istanbul Eurasia

INTRODUCTION[|]Seasonal and weather changes may affect the development of pulmonary embolism. The effects of seasonal and meteorological factors on mortality are controversial. We aimed to investigate the effects of seasons and meteorological data on patients with a low and high pulmonary embolism severity index and those with 30-day mortality. [¤]METHODS[|]Pulmonary embolism cases were included in our study. Daily pressure, humidity, temperature, and wind values were taken from the general online information by the Directorate of Meteorology. All cases were divided into the low-risk and high-

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Negative / Null Result ReportOpen accessMedicine

Low-dose oral pregabalin is not effective enough to control the acute post-thoracotomy pain

Swati Dogra , Altaf Hussain Mir , Suhail Sidiq et al. · 2025 · Asian Journal of Medical Sciences

Background: Acute post-thoracotomy pain (APTP) is severe and can lead to various respiratory complications if left untreated. Epidural (Ep) analgesia is the gold standard for APTP relief. Aims and Objectives: The aims and objectives of this study were to study the impact of low-dose oral pregabalin 75 mg on APTP. Materials and Methods: 100 patients were randomized into two groups (Group P and C). The Group P, study group received pregabalin 75 mg per oral preoperatively and for 2 days postoperatively. Group C received no medication. All the patients received thoracic Ep as a standard practice.

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Negative / Null Result ReportOpen accessMedicine

Obturator or "lateral" bypass in the management of infected vascular prostheses at the groin

Davidović Lazar B., Kuzmanović Ilija B., Kostić Dušan M. et al. · 2002 · Srpski Arhiv za Celokupno Lekarstvo

The infection of the previously implanted vascular graft at the groin, is associated with great mortality and morbidity rate [1]. The authors present a retrospective study in which they analyzed management of infected vascular prostheses at the groin, using obturator bypass in 26 cases, and "lateral" bypass in 15 cases. The indications for obturator bypass reconstructions included: 20 infections of aorto-femoral grafts, two infected pse udoaneurysms in the groin after RTA of the superficial femoral artery, and 4 infections of iliac-femoral grafts. The indications for lateral bypass reconstruct

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Negative / Null Result ReportOpen accessMedicine

Origins of the obturator artery in Thai and Chinese

Damkoeng Purnindu · 2023 · Siriraj Medical Journal

Dissection of one-half of adult pelvis in 197 Thai and 44 Chinese cadavers disclosed that the obturator artery arose from the internal iliac and umbilical arteries in 34.9%, from the inferior gluteal artery in 10.4%, from the internal pudendal artery in 8.7%, from the superior gluteal - inferior gluteal trunk in 4.2%, from the inferior gluteal - internal pudendal trunk in 9.1%, from the inferior epigastric artery in 12.0%, from the external iliac artery in 1.2%, and from the superior gluteal and the inferior epigastric arteries in 0.4%. There were no statistically significant differences of fi

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Negative / Null Result ReportOpen accessMedicine

Correlation of body mass index and orthostatic hypotension in patients with hypertension on ACE inhibitor monotherapy

Tasić Danijela, Kovačević Zorana, Mitrović Miroslav et al. · 2021 · Scripta Medica

Background/Aim: Orthostatic hypotension (OH) is considered to be a drop in the systolic and diastolic blood pressure (> 20 mmHg; > 10 mmHg) 3 minutes from postural changes. The objective of this study was to analyse the correlation of body mass index (BMI) and OH during the treatment with trandolapril, as a single-drug treatment of hypertension. Methods: The study involved 255 patients (average age 54.3 ± 11.7; 54.1 % men) with poorly regulated hypertension, who were given trandolapril as a single-drug treatment. The patients were divided into two groups regarding stage of hypertension: first-

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Negative / Null Result ReportOpen accessMedicine

Impact of an Online Gastrointestinal Symptom History Taker on Physician Documentation and Charting Time: Pragmatic Controlled Trial

Hall, Natalie J, Berry, Sameer K, Aguilar, Jack et al. · 2021 · JMIR Formative Research

BackgroundA potential benefit of electronic health records (EHRs) is that they could potentially save clinician time and improve documentation by auto-generating the history of present illness (HPI) in partnership with patients prior to the clinic visit. We developed an online patient portal called AEGIS (Automated Evaluation of Gastrointestinal [GI] Symptoms) that systematically collects patient GI symptom information and then transforms the data into a narrative HPI that is available for physicians to review in the EHR prior to seeing the patient. ObjectiveThis study aimed to compare whether

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Negative / Null Result ReportOpen accessMedicine

Is pomegranate peels infusion effective for disinfection of toothbrushes?

Priscila Lima de Luna FREIRE, Priscila Hernández CAMPOS, Fabíola Galbiatti CARVALHO et al. · Revista de Odontologia da UNESP

Abstract Introduction Methods of decontamination or sanitization of toothbrushes have been questioned. Objective This study assessed the effectiveness of pomegranate peels infusion as a disinfectant of toothbrushes against Streptococcus mutans. Material and method A sample of 16 schoolchildren aged between 7 and 9 years performed brushing 5 days/week, with a careful brushing once a day. After each day of brushing, the toothbrushes were washed and sprayed with one disinfectant solution. This procedure was repeated for 4 weeks using one of the different solutions per week: distilled water (G1; n

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Negative / Null Result ReportOpen accessMedicine

How safe and effective is oral analgesia for hip fracture patients? – a prospective cohort study

Zehra Abdul Muhammad, Tashfeen Ahmad · 2025 · Journal of the Pakistan Medical Association

Objective: To assess the safety and pain reduction profile of routinely prescribed oral analgesics in patients of hip fracture surgery. Method: The single-centre, prospective, cohort study was conducted from June 2022 to July 2023 at the Aga Khan University Hospital, Karachi and comprised adult patients of either gender with hip fractures. The analgesics prescribed at the time of hospital discharge and 1-week follow-up were recorded along with pain and adverse effects till the 2-week post-discharge follow-up. Pain was recorded using the visual analogue scale, with the target score set at 3/10.

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Negative / Null Result ReportOpen accessMedicine

Effects of executive function training on balance and auditory-cognitive dual-task performance in adults with and without hearing loss.

Niroshica Mohanathas, Lianna Montanari, Rachel Downey et al. · 2026 · PLoS ONE

Background Multitasking, such as listening while balancing, relies on integrated processing in the sensory, cognitive, and motor systems; systems that often decline with age. Hearing loss is linked to increased risks of both falls and cognitive decline. Improving cognitive processing through executive function (EF) training may support balance, especially in older adults with hearing loss. This randomized controlled study conducted across age groups and hearing abilities, examined the effects of a 12-week EF training program on postural outcomes (center of pressure (COP)) using an auditory-cog

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Negative / Null Result ReportMedicine

Preoperative blood spinal cord barrier biomarker levels correlate with neurological outcome in patients with degenerative cervical myelopathy one year after surgery: a prospective cohort study.

Schmidt TP, Jütten K, Bertram U et al. · 2026 · World neurosurgery

Degenerative cervical myelopathy (DCM) is the leading cause of chronic spinal cord dysfunction and can lead to severe neurological impairment if untreated. While decompressive surgery is the standard treatment, predicting postoperative…

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Negative / Null Result ReportMedicine

Causal Impact of Primary Care and Publicly Funded Health Insurance on Catastrophic Health Spending From Climate-Sensitive Diseases in India.

Chaudhary D, Mukhopadhyay I · 2026 · Applied health economics and health policy

Background Universal health coverage has become central to health policy debates, particularly as a strategy to protect households from financial hardship and impoverishment related to out-of-pocket (OOP) spending. Many low- and…

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Negative / Null Result ReportOpen accessMedicine

The mediating role of job and life satisfaction in the effect of psychological resilience on employee performance: evidence from the February 6 Kahramanmaraş (Türkiye) earthquakes.

Amırlı H, Gurbanli E · 2026 · BMC psychology

The purpose of this study is to investigate the mediating roles of job satisfaction (JS) and life satisfaction (LS) in the relationship between psychological resilience (PR) and employee performance (EP). Data for this study, which…

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Negative / Null Result ReportMedicine

The combined and independent influence of food texture and a 'mindful eating' instruction on eating rate and food intake among Dutch primary schoolchildren.

Jager G, de Wild VWT, Camps G et al. · 2026 · Appetite

Eating rate (ER), the amount of food consumed per unit of time, is a key determinant of food intake, with faster ER associated with larger meal size. Research in adults has shown that both sensory properties like texture, and instructions…

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Negative / Null Result ReportMedicine

Mpox therapeutics in the post-STOMP/PALM era.

Promer K, Brenner SB, Ostrer L et al. · 2026 · Current opinion in HIV and AIDS

Purpose of review This article reviews the evidence behind mpox antiviral therapies which are clinically available and/or or under clinical investigation. For much of the mpox epidemic, tecovirimat has been used compassionately but there…

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Negative / Null Result ReportMedicine

Neopterin Levels in Pediatric Allogeneic Hematopoietic Stem Cell Transplantation: A Potential Biomarker for Acute Graft-Versus-Host Disease?

Kirkiz Kayalı S, Deveci TS, Gülbahar Ö et al. · 2026 · Transplantation proceedings

Introduction Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment for hematologic disorders. Acute graft-versus-host disease (aGVHD) remains a major cause of nonrelapse mortality. Distinguishing aGVHD from…

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Negative / Null Result ReportMedicine

Efficacy and safety of tirofiban after successful endovascular reperfusion in acute ischaemic stroke (ATTRACTION) in China: a multicentre, double-blind, randomised controlled trial.

Huang, Xu, Qin et al. · 2026 · Lancet (London, England)

Successful reperfusion after endovascular thrombectomy does not consistently result in functional independence in acute ischaemic stroke. We aimed to assess the efficacy and safety of tirofiban, a glycoprotein IIb/IIIa receptor antagonist,…

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Negative / Null Result ReportMedicine

Management of stiffness after total knee arthroplasty: influence of intervention timing and surgical technique on clinical outcomes.

Peretó Villaescusa, Coelho, Grillo et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

Postoperative knee stiffness following total knee arthroplasty (TKA) is a challenging complication that may require surgical intervention when conservative treatment fails. Although manipulation under anesthesia (MUA) and arthroscopic…

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Negative / Null Result ReportMedicine

Comparison of the effectiveness of 30% Aloe vera cream and 20% urea cream as topical treatment for xerosis cutis in chronic kidney disease: a randomized clinical trial.

Fajriani, Djawad, Tabri et al. · 2026 · Dermatology reports

Xerosis is a prevalent skin disorder among patients with chronic kidney disease (CKD) undergoing hemodialysis (HD). While both Aloe vera cream 30% and urea cream 20% have been shown to improve skin hydration in cases of xerosis cutis,…

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