11,312 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Jang S, Kim D, Kim T et al. · 2025 · Nanotechnology
In this study, a Cleaning Endpoint Evaluation Sensor (CEES) was developed and applied to improve the monitoring accuracy and uniformity control in the cleaning processes for NF 3 -based remote plasma sources in semiconductor equipment.…
View details →Wang J · 2025 · Scandinavian journal of trauma, resuscitation and emergency medicine
This comment critiques a trial comparing intranasal dexmedetomidine (DEX) and esketamine (sKET) for pediatric procedural sedation. Despite a large effect size, the small sample (n = 29) likely caused false-negative results (p = 0.09),…
View details →Bacon EK, Parnell D, Muscatello G et al. · 2025 · Journal of equine veterinary science
Background The ongoing discussion surrounding the well-being of retired racehorses underscores the importance of implementing effective rehoming strategies that prioritise animal welfare. A significant knowledge gap persists regarding…
View details →Seidel M, Barns H, Klostermann C et al. · 2025 · Journal of Nutrition Education and Behavior
Nationwide, 41% - 48% of students on college campuses are food insecure (FI). These students are more likely to do poorly in school and drop out than their food secure (FS) peers. In 2017, 30% of students at Chatham University (CU), a…
View details →Lang A, Gabriel H, Meister TL et al. · 2026 · The Journal of hospital infection
Background Candida (Candidozyma) auris is a globally emerging multidrug-resistant fungal pathogen that causes nosocomial outbreaks in healthcare facilities. Aim To evaluate the susceptibility of different C. auris clade strains (I to V)…
View details →Felicioni F, Nivia-Riveros JA, Caldeira-Brant AL et al. · 2026 · The Journal of nutritional biochemistry
Proper fetal development depends on maternal nutrition. We investigated the placental morphofunctional adaptations to a low-protein diet, and their impact on fetal and newborn outcomes. Swiss mice were fed either normal (NPD, 20% crude…
View details →Boles B, Gardner JA, Rehder CW et al. · 2025 · Archives of pathology & laboratory medicine
Context.— The joint College of American Pathologists/American College of Medical Genetics and Genomics Cytogenetics Committee works to ensure competency and proficiency of clinical cytogenetics testing laboratories through proficiency…
View details →Tsuchie R, Hashimoto Y, Abiko M et al. · 2026 · Neurologia medico-chirurgica
Anatomical variations in the middle cerebral artery affect outcomes of mechanical thrombectomy in M1 occlusion cases. However, the relationship between middle cerebral artery branching patterns-specifically trifurcation and bifurcation-and…
View details →Umeaghadi CF, Taylor JG, Yao S et al. · 2026 · Patient preference and adherence
Adherence surveys can be lengthy due to the high number of potential risk factors to be analyzed. As a result, researchers often reduce items into conceptual domains (eg, beliefs, economic factors) to overcome power constraints or focus…
View details →Eckert L, Miller JS, Fitzpatrick JL et al. · 2025 · Evolution; international journal of organic evolution
Reproductive accessory glands are organs involved in reproduction that do not directly produce or release gametes but can play crucial roles in securing reproductive success. In fishes, the 2 leading hypotheses about why accessory glands…
View details →Mo M, Xie J, Wu C et al. · 2026 · Frontiers in nutrition
Background Enteral nutrition (EN) in septic shock patients is a double-edged sword. The impact of early enteral nutrition (EEN) on mortality in septic shock patients remains uncertain, and whether this association is modified by…
View details →Sisk BA, Antes AL, Bereitschaft C et al. · 2025 · The Journal of adolescent health : official publication of the Society for Adolescent Medicine
Purpose United States healthcare systems have enacted varied adolescent online patient portal policies. No prior work has established whether these policies are acceptable to adolescents and parents. Methods Mixed-method Delphi approach…
View details →Harada Y · 2026 · Cureus
Introduction Large language models are increasingly discussed as tools for patient-facing symptom assessment, but safe self-triage depends on the concrete next action recommended to the user rather than on generic urgency language alone.…
View details →Lin CY, Liao WL, Lin HJ et al. · 2025 · Eye & contact lens
Purpose To compare the ocular comfort and tear film stability of low viscous and medium viscous lubricant eye drops in orthokeratology lens users. Method This is a prospective, two-arm, randomized, crossover trial. After a 7±2 day run-in…
View details →Romeo DJ, Wagner CS, Ahluwalia V et al. · 2025 · The Journal of craniofacial surgery
Many people living in low-income and middle-income countries (LMICs) lack access to safe surgical and anesthetic care. The Lancet Commission on Global Surgery (LCGS) recommended that all countries track surgical volume and target 5,000…
View details →Park SJ, Park JS, Kang DH et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Purpose To identify factors associated with failure to achieve the minimal clinically important difference (MCID) in the Scoliosis Research Society-22r (SRS-22r) despite achieving optimal global alignment in adult spinal deformity (ASD)…
View details →Drew RH, Turner NA, Keil E et al. · 2026 · Infection control and hospital epidemiology
In a propensity-matched cohort of adult cardiac or neurosurgical procedures ( n = 1,342), infection was less frequent with continuous infusion (1.8%) versus intermittent cefazolin (2.4%), though the difference was statistically…
View details →Schmitt A, Behnes M, Bertsch T et al. · 2025 · European journal of internal medicine
Background Elevated uric acid (UA) is a recognized biomarker in patients with cardiovascular disease. However, the prognostic significance of UA levels in patients with heart failure (HF), particularly those with HF with mildly reduced…
View details →Fortunato C, Gasperini B, Mengarelli Rinaldini D et al. · 2025 · Annali di igiene : medicina preventiva e di comunita
Background Vaccine hesitancy is considered one of the top ten threats to global health by the World Health Organization due to the potential public health consequences. Since April 1, 2021, the Italian Government has made COVID-19…
View details →Ellis LR, O'Connor D, Khan H et al. · 2026 · European journal of nutrition
Purpose Despite equivocal human study data, anthocyanin-rich blueberries are associated with positive glycaemic effects which could benefit satiety and other cardiometabolic outcomes. The objective of this study was to examine the…
View details →Joseph Varughese V, Richardson C, Pollock J et al. · 2025 · Medicina (Kaunas, Lithuania)
Background and Objectives : MitraClip ® (MC) placement has been extensively used as an intervention for mitral transcatheter edge-to-edge repair (mTEER) for functional mitral regurgitation (FMR). The aim of our study is to analyze the…
View details →Chimowitz MI · 2026 · Stroke
CREST-2 (Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trials) comprised 2 parallel randomized trials in asymptomatic carotid stenosis comparing medical management alone with medical management plus…
View details →Balakrishnan P, Saravanan S, Vignesh R et al. · 2025 · Indian journal of medical microbiology
Background Hepatitis C virus (HCV) is still a serious public health issue because it can cause cirrhosis, hepatocellular carcinoma (HCC), and chronic hepatitis. In almost 70 % of cases, HCV infection results in chronic persistence, which…
View details →Rezaie MJ, Allahveisie A, Nikkhoo B et al. · 2025 · International journal of fertility & sterility
Background Oocyte in vitro maturation (IVM) is a valuable technology applied to acquire fully developed oocytes for several clinical purposes. Despite substantial research on optimizing culture media, the success rate of IVM remains low.…
View details →Lindqvist J, Askling J, Lampa J · 2023 · RMD open
Objective To assess associations between inflammatory remission, formal treatment targets and the likelihood of starting a new disease-modifying antirheumatic drug (DMARD), among patients with early rheumatoid arthritis (RA). Methods…
View details →Wilkinson T, Booth K · 2025 · The Surgical clinics of North America
The management of perianal Crohn's disease is challenging and complex and requires a multidisciplinary approach as a favorable working relationship between gastroenterologists and colorectal surgeons is necessary to provide excellent care…
View details →Hom B, McIntee D, Zhang YP et al. · 2025 · Saudi journal of anaesthesia
Background Ketamine has been shown to be an effective treatment at sub-anesthetic doses for various chronic pain conditions. This study assesses the relationship between oral ketamine and the incidence of adverse side effects in patients…
View details →Garg A, Strunk A, Midgette B et al. · 2026 · JAMA dermatology
Importance Accurate classification and reliability in assessment for lesions of hidradenitis suppurativa (HS) by investigators is critical to the determination of responder status and to overall data quality in clinical trials. Objective…
View details →Estudillo AJ, Dark O, Wiener JM et al. · 2025 · Brain sciences
Background/Objectives: Previous studies have reported associations between prosopagnosia and spatial navigation, but it remains unclear whether this link is merely coincidental (i.e., observable only in prosopagnosia) or genuinely…
View details →Li H, Hao W, Maeda E et al. · 2025 · Reproductive biomedicine online
Research question Are physical activity and sedentary time associated with the DNA fragmentation index (DFI) score and conventional semen parameters in healthy Japanese men? Design Baseline data from the Preconception Research and…
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