Negative / Null Result ReportOpen accessMedicine
Hashem Heshmati, Karim darvishpour · 2015 · مجله ایرانی آموزش در علوم پزشکی
Introduction: Clinical education is one of the most important aspects of medical and paramedical students' education and has a determining role in the professional future of these students as well as other professionals in health care. So this study aimed to evaluate the effective factors in the quality of clinical education from the viewpoints of operation room and Anesthesiology students in Torbat Heydarieh University of Medical Sciences. Methods: In this descriptive cross-sectional study, a number of 115 students of operation room and Anesthesiology studying in Torbat Heydarieh university o
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Bohan Jia, Junyi Sun, Di Zhu et al. · 2025 · Scientific Reports
Abstract Cancer significantly contributes to the unfavorable prognosis of coronavirus disease 2019 (COVID-19) patients. The efficacy and safety of azvudine and nirmatrelvir/ritonavir (Paxlovid) in cancer patients with COVID-19 remain uncertain. Therefore, we designed a comprehensive retrospective study encompassing clinical data of 32,864 hospitalized COVID-19 patients, 691 of whom were cancer patients treated with azvudine and 200 were cancer patients treated with Paxlovid. After 2:1 propensity score matching, 397 patients in the azvudine group and 199 patients in the Paxlovid group were enro
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Zagorac Slaviša, Bumbaširević Marko, Lešić Aleksandar et al. · 2008 · Srpski Arhiv za Celokupno Lekarstvo
Introduction Multiple trauma is one of the leading causes of mortality and morbidity in the population of people under 45 years of age. The consequences of multiple trauma have huge epidemiological, social and economic significance. Objective The aim of the paper was to analyze the conclusive treatment outcome of multiply traumatized patients with respect to their sex, age, injury mechanism and type. METHOD This retrospective study included 100 patients with multiple injuries (ISS>16) treated in the Emergency Room of the Clinical Centre of Serbia in the course of 2004. Clinical, X-ray, laborat
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Levent Cigerim, Erkan Feslihan · 2019 · Journal of Oral Health and Oral Epidemiology
BACKGROUND AND AIM: Alterations in blood pressure (BP) and variability of heart rate (HR) throughout dental procedures were not clearly understood. The aim of this study is to evaluate the effects of body mass index (BMI) on BP and HR in patients undergoing tooth extraction. METHODS: Based on BMI, 831 patients who underwent single tooth extraction were divided into two groups; group 1: underweight and normal-weight patients, group 2: overweight and obese patients. BP and HR were monitored before local anesthesia and after tooth extraction. For statistical analysis of the data, Number Cruncher
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Kyung-Hee Cho, Seol-Hee Baek, Sung-Hee Kim et al. · 2024 · The Journal of Headache and Pain
Abstract Background Currently, there is a relative lack of detailed reports regarding clinical presentation and outcome of idiopathic intracranial hypertension in Asians. This study aims to describe the clinical features and treatment outcomes of Korean patients with idiopathic intracranial hypertension. Methods We prospectively recruited patients with idiopathic intracranial hypertension from one hospital and retrospectively analyzed the medical records of 11 hospitals in Korea. We collected data regarding preceding medical conditions or suspected medication exposure, headache phenotypes, oth
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Sonia Rekik, Hela Sahli, Khaoula Zouaoui et al. · 2022 · F1000Research
Background: Digital gangrene is a rare but serious complication of systemic lupus erythematosus (SLE). It occurs usually in middle-aged patients with longer disease duration. Case: Herein we report the case of a 56-year-old man (with no history suggestive of Raynaud’s phenomenon, diabetes mellitus, smoking, trauma, infection, or chemical exposure), who presented with SLE and digital gangrene was among the first signs. He presented with a one-month history of joint pain, hair loss, photosensitivity, mouth ulcers, malar rash, dyspnea, and digital pain. Physical examination revealed painful and d
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Edward C. Y. Liew, Maureen Phelan, Keith L. McDougall · 2023 · Scientific Reports
Abstract Phytophthora cinnamomi is an oomycete found in the soil and capable of invading the roots of a wide range of host plants globally, potentially killing them and affecting the ecosystems they inhabit. This pathogen is often inadvertently dispersed in natural vegetation on the footwear of humans. A range of equipment is often provided or recommended to be carried for cleaning footwear in places where P. cinnamomi poses a threat to biodiversity. These are typically a brush for mechanically removing soil and/or a disinfectant for killing the pathogen. Despite their widespread use, to our k
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Kute, Fujino, Centauri et al. · 2026 · Experimental and therapeutic medicine
Ultra-low anterior resection (ULAR) and total mesorectal excision (TME) are sphincter-preserving treatments for low rectal cancer. However, these techniques face challenges in patients with a narrow pelvis, particularly those with a high…
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Anusuya, Balaji, Manikandan · 2026 · Journal of Indian Society of Periodontology
Periodontal regeneration aims to restore the natural structure of the periodontium, therefore improving the long-term stability and function of the affected teeth. Traditional bone graft materials such as allografts, autografts,…
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Reda, Ollaek, Mostafa et al. · 2026 · Anaesthesia reports
Open total abdominal hysterectomy is associated with substantial postoperative pain. We compared ultrasound-guided transversus abdominis plane block with ilioinguinal-iliohypogastric nerve block for postoperative analgesia. We conducted a…
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Kwak N, Kim JY, Kim HJ et al. · 2025 · Tuberculosis and respiratory diseases
Background This study aimed to determine whether a shorter high-dose rifampicin regimen is non-inferior to the standard 6-month tuberculosis regimen. Methods This multicenter, randomized, open-label, non-inferiority trial enrolled…
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Rosamund Chapman, Michiel van Diepen, Shireen Galant et al. · 2020 · Vaccines
The HIV-1 envelope glycoprotein (Env) is present on the surface of the virion at a very low density compared to most other enveloped viruses. Substitution of various parts of the stalk domain of Env (gp41) with the corresponding elements from other viral glycoproteins has been shown to increase Env spike density on the cell membrane and surface of virus-like particles (VLPs). In this study, chimeric Env antigens were generated by replacing the transmembrane and cytoplasmic domains of HIV-1 Env with the corresponding regions from the influenza H5 hemagglutinin (HA) (gp140HA 2 tr) and by replaci
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Da Jun Than, Vinodh Vayara Perumall, Syamim Johan et al. · 2023 · Einstein (São Paulo)
ABSTRACT Post-thoracotomy paraplegia after non-aortic surgery is an extremely uncommon complication. A 56-year-old woman presented with a 1-year history of progressive shortness of breath. Computed tomography revealed a locally advanced posterior mediastinal mass involving the ribs and the left neural foramina. Tumor excision with a left pneumonectomy was performed. Post-resection, bleeding was noted in the vicinity of the T4-T5 vertebral body, and the bleeding point was packed with oxidized cellulose gauze (Surgicel®). Postoperatively, the patient complained of bilateral leg numbness extendin
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M. I. Lourenço-Silva, A. Ulans, A. M. Campbell et al. · 2023 · Scientific Reports
Abstract Impacts of environmental complexity on affective states in slow-growing broiler chickens (Gallus gallus domesticus) are unknown. Chickens’ performance in judgment bias tests (JBT) can be limited as they are tested individually, causing fear and anxiety. The objectives were to apply a social-pair JBT to assess the effect of environmental complexity on slow-growing broiler chickens` affective states, and assess the impact of fearfulness, anxiety, and chronic stress on JBT performance. Six-hundred Hubbard Redbro broilers were housed in six low-complexity (similar to commercial) or six hi
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Mottaghi T, Askari Gh, Khorvash F et al. · 2015 · مجله دانشگاه علوم پزشکی گرگان
Background and Objective: Migraine is common worldwide. In recent years, vitamin D deficiency has been shown as a global health issue. This study was done to determine the relationship between serum levels of vitamin D with migraine. Methods: This descriptive - analytical study was carried out on 76 patients (21 males, 55 females) with migraine aged 10-61 years olds. Serum vitamin D level of each patient was measured. Adjustments were done for age, sex, waist circumference, body mass index (BMI), number of chronic diseases, and education level. The multiple linear regressions were done to dete
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Noriyuki Oka, Masaharu Sakoh, Misato Hirayama et al. · 2023 · Scientific Reports
Abstract The corticofugal tracts (CFT) are key agents of upper limb motor function. Although the tracts form high-intensity regions relative to surrounding tissue in T2-weighted magnetic resonance images (T2WI), the precise relations of signal intensities of the left and right CFT regions to hand function are unknown. Here, we tested the hypothesis that the different signal intensities between the left and right CFT signify clinically important differences of hand motor function. Eleven right-handed and eleven left-handed healthy volunteers participated in the study. Based on horizontal T2WI e
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Noura A. Almadhi, Ayman M. Sulimany, Hamad A. Alzoman et al. · 2021 · Saudi Dental Journal
Objective: To evaluate parents’ knowledge about halitosis, and to compare parents’ perception of halitosis in their children to the presence of halitosis clinically. Methods: Children between 3 and 8 years attended to Dental University Hospital, King Saud University, were screened. Children satisfying inclusion criteria and their parents agreed to participate were included. Questionnaires regarding parents’ knowledge and perception about halitosis in their children were filled by attending parents. Then, the assessment of halitosis in the participating children carried out by portable gas chro
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Patil PB, Chougule PG, Kamat SB et al. · 2026 · Journal of conservative dentistry and endodontics
Aim The aim of this in vitro study was to evaluate the effect of antacid syrup on surface roughness and microhardness of composites. Materials and methods Two different composite resin materials, Nanofilled and Suprananofilled were used.…
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Marjolein M Iversen, Giesje Nefs, Grethe S Tell et al. · 2016 · PLoS ONE
Aim To examine whether elevated anxiety and/or depressive symptoms are related to all-cause mortality in people with Type 2 diabetes, not using insulin. Methods 948 participants in the community-wide Nord-Trøndelag Health Survey conducted during 1995-97 completed the Hospital Anxiety and Depression Scale with subscales of anxiety (HADS-A) and depression (HADS-D). Elevated symptoms were defined as HADS-A or HADS-D ≥8. Participants with type 2 diabetes, not using insulin, were followed until November 21, 2012 or death. Cox regression analyses were used to estimate associations between baseline e
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Stokbro, Liebregts, Baan et al. · 2026 · Scientific reports
The aim of this study was to evaluate the influences of surgical sequencing on the postoperative occlusion in bimaxillary osteotomies. Patients who underwent bimaxillary surgery without maxillary segmentation, based on a virtual surgical…
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Paschalina C Ezechukwu, Emmanuel O Ugwu, Samuel N Obi et al. · 2023 · International Journal of Medicine and Health Development
Background: Preeclampsia is one of the leading causes of maternal and perinatal morbidity and mortality in Nigeria and worldwide. It is not yet concluded as to whether or not elevated levels of serum creatinine and/or uric acid could be regarded as a predictive indicator for the severity of the disease. Objectives: To compare the mean serum levels of uric acid and creatinine in preeclamptic and normotensive pregnant women and assess for any associations between these renal biomarkers and the severity of preeclampsia in Nigeria. Materials and Methods: It was a cross-sectional analytical study o
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Kibum Kim, Linda Kaitlyn Craft · 2022 · BMJ Open
Objective Non-invasive prenatal testing (NIPT) is a front-line screening for fatal chromosomal aneuploidy. In pregnant women with a risk of having fetal congenital disorders, NIPT is anticipated to reduce the needs of invasive prenatal diagnostic test (IPD). The objective of this study was to understand the acceptance of NIPT and the utility of NIPT to mitigate concerns about IPD in the US high-risk pregnancy management.Design and setting This was a retrospective observational research using healthcare records obtained from an academic healthcare system in the US. The study consisted of site-l
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Haure Osman Muhammad Hamadamin, Samir Mahmood Othman · 2026 · Zanco Journal of Medical Sciences
Background and objective: Obesity is a chronic, multifactorial condition characterized by an excessive accumulation of body fat that presents significant health risks. Community pharmacists, for instance, are highly accessible and often serve as the first point of contact for patients seeking advice on weight management. This study aims to fill a research gap by evaluating community pharmacists’ knowledge, attitudes, and practices related to obesity and weight management. Methods: A cross-sectional study was carried out among 331 community pharmacists among different pharmacy settings in Erbil
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Michinobu Umakoshi, Akiko Nakamura, Hiroyuki Tsuchie et al. · 2023 · Scientific Reports
Abstract Even when treated comprehensively by surgery, chemotherapy, and radiotherapy, soft-tissue sarcoma has an unfavorable outcome. Because soft-tissue sarcoma is rare, it is the subject of fewer clinicopathological studies, which are important for clarifying pathophysiology. Here, we examined tumor-associated macrophages in the intratumoral and marginal areas of sarcomas to increase our knowledge about the pathophysiology. Seventy-five sarcoma specimens (not limited to a single histological type), resected at our institution, were collected, and the number of CD68-, CD163-, and CD204-posit
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N Bushra Thasneem, Resmi S. Kaimal, Abdul Hakeem Thengu Murichathil · 2025 · Journal of Family Medicine and Primary Care
Introduction: Anaemia is one of the significant public health problems faced by developing countries. It occurs more frequently in women of childbearing age. Anaemia causes poor work capacity, and severe forms may even cause cardiac failure. In pregnant women, anaemia may lead to preterm labour, low-birth-weight babies, and increased risk of maternal mortality due to post-partum haemorrhage. Even though there are national programmes to supply iron free of cost and other measures to tackle anaemia, it is still prevalent in our country. Anaemia prevalence has increased between NFHS-4 and NFHS-5,
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Muhammad Hussain Iqbal, Tanveer Hussain, Fariha Khalid et al. · 2020 · Pakistan Armed Forces Medical Journal
Objective: To determine the frequency of diastasis recti abdominis and its associated risk factors in postpartum women. Study Design: Cross-sectional study. Place and Duration of Study: Omar Medical Center Lahore, Yaseen Medical Center Lahore and Social Security Hospital Lahore, from Sep 2019 to Dec 2019. Methodology: This study included 128 participants fulfilling the eligibility criteria. The assessment of diastasis recti abdominis was done manually by a female physiotherapist using single finger, double finger and three finger methods on abdomen at three levels: at the umbilicus, 4.5 cm bel
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Abida Shaheen, Syed Mahboob Alam, Fahad Azam et al. · 2022 · PLoS ONE
Background and objective Gabapentinoids are the first-line drugs for neuropathic pain. These drugs are the substrate of organic cation transporter (OCTN1) for renal excretion and absorption across the intestinal epithelium. Gabapentinoids exhibit wide interindividual variability in daily dosage and therapeutic efficacy which makes titration regimens prolonged for optimal efficacy. The present study aimed to investigate the possible influence of the single nucleotide polymorphism (SNP) of OCTN1 on therapeutic efficacy and safety of gabapentinoids in neuropathic pain patients of the Pakistani po
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Al-mustafa Mahmoud, Massad Islam, Alsmady Moaath et al. · 2010 · Saudi Journal of Kidney Diseases and Transplantation
Vertical infraclavicular brachial plexus block is utilized in patients with chronic renal failure at the time of creation of an arterio-venous fistula (AVF). The aim of this study is to test the effect of impaired renal function, with the resulting deranged serum electrolytes and blood gases, on the success rate and the onset of action of the local anesthetics used. In this prospective clinical study, we investigated the effect of the serum levels of sodium, potassium, urea, crea-tinine, pH, and bicarbonate on the onset of action of a mixture of lidocaine and bupivacaine administered to create
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Selma Celen Yuceturk, Sumeyye Aydogan Turkoglu, F. Kockar et al. · 2021 · Zeitschrift für Naturforschung C - A Journal of Biosciences
Abstract In this study, the chemical composition, antimicrobial, antioxidant, and anticancer effects of Thymus convolutus Klokov oil and its main compound camphor were investigated. The oil was isolated from T. convolutus using…
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Ayman Mohammed Baabdullah, Abdulmalik Ghassan Abumohssin, Yara Aedh Alqahtani et al. · 2019 · Journal of Nature and Science of Medicine
Background: The use of smartphones has increased exponentially. Excessive usage of smartphones has been shown to have a negative impact on ocular health. This study aimed to evaluate the relationship between smartphone addiction and dry eye disease (DED) and determine the risk factors of DED in participants associated with smartphone addiction. Materials and Methods: This cross-sectional study was conducted in May 2017. Participants were selected from the Faculty of Medicine at King Abdulaziz University in Jeddah, Saudi Arabia. Stratified random sampling technique was used to recruit participa
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