11,312 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Bakare AB, Lee Y, Hong J et al. · 2026 · Health care science
Background Assess ChatGPT and Bard's effectiveness in the initial identification of articles for Otolaryngology-Head and Neck Surgery systematic literature reviews. Methods Three PRISMA-based systematic reviews (Jabbour et al. 2017, Wong…
View details →Hertereau L, Barthe M, Lamghari N et al. · 2026 · JID innovations : skin science from molecules to population health
The distribution of receptors and cellular factors across tissues determines differential susceptibility of cells to viral infection. For severe acute respiratory syndrome coronavirus 2, viral spike and nucleocapsid proteins have been…
View details →Naoe S, Ubukata M, Tsunamoto Y et al. · 2025 · Plant species biology
Vertical seed dispersal, involving seed movement to higher or lower elevations, plays a vital role in plant adaptation to rising temperatures. However, its assessment has been limited owing to labor‐intensive processes. A recently…
View details →Bhise M, Anandani G, Goswami P et al. · 2025 · Bioinformation
Malaria remains a major public health concern and accurate diagnosis is essential for effective management. This retrospective study compared the diagnostic performance of immunochromatographic rapid diagnostic tests (RDT) and peripheral…
View details →Sani LM, Senjarini K, Steinke S et al. · 2025 · Diagnostic microbiology and infectious disease
Background Dengue virus (DENV) is a major public health concern in Indonesia, with all four serotypes contributing to recurrent outbreaks. This study evaluated molecular diagnostic tests for DENV and identified circulating serotypes…
View details →Yu Z, Abdel-Azim S, Duggal P et al. · 2025 · BMC genomics
Background Acute infection with hepatitis C virus (HCV) affects millions of individuals worldwide. Host genetics plays a role in spontaneous clearance of the acute infection which occurs in approximately 30% of the individuals. Common…
View details →Elmahdy A, Krasnikova M, Jha A et al. · 2025 · Scientific reports
Ischemic preconditioning (PreC), remote perconditioning (PerC), and postconditioning (PostC) are known to reduce myocardial infarct size, but their relative efficacy and potential additive effects remain unclear. This study compared the…
View details →Lalonde RJ, Keller A, Huq S · 2021 · International journal of radiation oncology, biology, physics
Purpose/objective(s) Previous studies have suggested that the dose immediately outside the PTV may impact the incidence of distant metastases after stereotactic body radiation therapy (SBRT) for patients with early-stage non-small cell…
View details →Lorenz S, Bartusch L, Heusler C et al. · 2026 · Clinical neurophysiology practice
Objective To investigate whether transcranial static magnetic stimulation (tSMS) exerts inhibitory effects on the human motor cortex and whether these effects differ between dominant and non-dominant hemispheres. Methods Participants…
View details →Batra D, Chen M, Meis J et al. · 2025 · Neurological research and practice
Background Endovascular thrombectomy (EVT)-often combined with intravenous thrombolysis-is the standard of care for acute ischemic stroke (AIS) secondary to large vessel occlusions (LVO). While indications keep expanding, the feasibility…
View details →Asiimwe R, Welch T, Dwanyen L et al. · 2026 · Family process
The influence of father positive parenting and involvement on children's mental health outcomes is underexplored in many sub-Saharan African countries, such as Uganda, despite research showing that fathers play a critical role in shaping…
View details →Griffioen G, Tangen Ä, Veldman E et al. · 2026 · EJNMMI research
BACKGROUND: Social cognition is impaired across multiple psychiatric disorders and varies dimensionally in the general population. Studying healthy adults can therefore inform mechanisms relevant for social cognition. This study aimed to…
View details →Cariveau T, La Cruz Montilla A · 2022 · Behavior modification
Differential reinforcement of a target response is a necessary component of stimulus control transfer procedures. Recent research has further considered the timing (i.e., onset) of differential reinforcement of unprompted correct…
View details →Bicona D, Mountford HS, Bridges EC et al. · 2025 · Behavior genetics
Literacy is a significant predictor of important life outcomes, such as attained education and income (Ritchie and Bates in Psychol Sci 24(7):1301-1308, 2013. 10.1177/0956797612466268) yet difficulties in reading and spelling are common.…
View details →De Luca A, Verschoor S, Hommel B · 2022 · Experimental psychology
Mood has been argued to impact the breadth of human attention, but the empirical evidence supporting this claim remains shaky. Gable and Harmon-Jones (2008) have attributed previous empirical inconsistencies regarding the effect of mood on…
View details →Chapman HA · 2021 · Emotion (Washington, D.C.)
Emotional stimuli modulate cognitive processes such as attention and memory to facilitate an adaptive response to the environment. For example, previous research suggests that fearful facial expressions broaden attention to help the…
View details →Kott A, Brannan S, Wang X et al. · 2023 · Schizophrenia bulletin open
Objectives We sought to evaluate the impact of baseline anxiety levels on drug placebo separation and drug and placebo response in acutely psychotic schizophrenic subjects. Methods In this post-hoc analysis, modified intent-to-treat…
View details →Suhre K, Chen Q, Halama A et al. · 2025 · Nature genetics
Most studies to date of protein quantitative trait loci (pQTLs) have relied on affinity proteomics platforms, which provide only limited information about the targeted protein isoforms and may be affected by genetic variation in their…
View details →Jhelum H, Schäfer R, Kaufer BB et al. · 2025 · Viruses
Porcine cytomegalovirus, more accurately classified as porcine roseolovirus (PCMV/PRV), was shown to be pathogenic in the context of xenotransplantation. Transmission of PCMV/PRV to non-human primates receiving hearts or kidneys from…
View details →Abuleil D, Gorbet D, McCulloch DL et al. · 2025 · Frontiers in neuroscience
Introduction Anodal direct current stimulation (a-tDCS) of the visual cortex is a potential rehabilitation tool for vision disorders such as amblyopia and macular degeneration. However, the underlying neural mechanisms are currently…
View details →Almajed N, Al-Musharaf S, Aldhwayan MM et al. · 2025 · International journal of general medicine
Purpose Certain trace minerals, such as zinc (Zn) and magnesium (Mg), may play a role in glucose regulation and insulin signaling pathways. However, population data from the Middle East are scarce and may differ in terms of dietary and…
View details →Herzig L, Stöckert J, Lochmann M et al. · 2026 · Frontiers in sports and active living
The aim of this study was to determine if positional Worst-Case-Scenarios (WCS) during official games (OG) are replicated in Large-Sided Games (LSG) with a similar Area per Player (ApP) as OG. Twenty-one football players from the second…
View details →Bugden S, Szkudlarek E, Brannon EM · 2021 · Trends in neuroscience and education
Background Prior studies reported that practice playing an approximate arithmetic game improved symbolic math performance relative to active control groups in adults and preschool children (e.g. Park & Brannon, 2013, 2014; Park et al.,…
View details →Schriefl C, Schoergenhofer C, Buchtele N et al. · 2022 · Journal of personalized medicine
Background The clinical value of a prognostic score depends on its out-of-sample validity because inaccurate outcome prediction can be not only useless but potentially fatal. We aimed to evaluate the out-of-sample validity of a recently…
View details →Daubney ER, Flatley C, Hwang LD et al. · 2025 · Behavior genetics
Despite significant advances in pre- and postnatal care over the last century, adverse pregnancy related events still occur frequently. We used Mendelian randomisation (MR) to investigate potential causal effects of the mother's and fetal…
View details →Groncki R, Beaudry JL, Sauer JD · 2021 · Memory (Hove, England)
The way in which individuals think about their own cognitive processes plays an important role in various domains. When eyewitnesses assess their confidence in identification decisions, they could be influenced by how easily relevant…
View details →Patel KR, Pugh SL, Simko JP et al. · 2026 · Advances in radiation oncology
Purpose The cyclin-dependent kinase inhibitor p27 is a well-profiled modulator of cell cycle progression. Low nuclear p27 levels have been demonstrated to have a negative prognostic impact on outcomes in patients undergoing prostatectomy.…
View details →Fu CK, Lee HT, Yang YC et al. · 2025 · In vivo (Athens, Greece)
Background/aim Gastric adenocarcinoma (GACA) remains a major global health concern, particularly in Asia, due to its poor prognosis and complex etiology. The interaction between genetic factors and environmental exposures, such as smoking,…
View details →Papadopoulos E, Rozenberg D, Wong AKO et al. · 2025 · PloS one
Background Skeletal muscle index (SMI), grip strength, and physical performance have been shown to predict clinically relevant outcomes in geriatric oncology. However, their predictive ability for chemotherapy toxicity is poorly…
View details →Centorame G, Warrington NM, Hemani G et al. · 2025 · Behavior genetics
Breastfeeding is hypothesised to benefit child health and cognitive functioning by providing long-chain polyunsaturated fatty acids, which are essential for brain development. In 2007, Caspi et al. found evidence in two cohorts for an…
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