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1 real negative results, null findings, and replication failures in Biotechnology · Replication Failure. Search the index →

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Replication FailureOpen accessBiotechnology

Sequential Bone Repair in Rabbit Sinus Lifts Using Bio-Oss and Hyaluronic Acid–Polynucleotide Gel (Regenfast)

Nozomi Maniwa, Samuel Porfirio Xavier, Sergio Luis Scombatti de Souza et al. · 2024 · Journal of Functional Biomaterials

Background: A comprehensive investigation to associate the use of polynucleotides and hyaluronic acid with bovine bone in maxillary sinus lift procedures in rabbits has not been performed yet. The aim was to evaluate the influence of this novel association on the processes of bone regeneration in maxillary sinus augmentation. Methods: In this prospective, randomized, within-animal model, maxillary sinus augmentation was performed bilaterally in 12 rabbits. Deproteinized bovine bone material (DBBM) was used as filler material. A hyaluronic acid–polynucleotide gel was aggregated at the test site

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