Adjunctive Therapies in Periodontitis: Current Concepts and the Future
Rafael Scaf de Molon; João Paulo Steffens; Érica Dorigatti de Ávila; Wim Teughels; Thomas E. Van Dyke · 2026 · Journal of Periodontal Research
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Periodontitis is a chronic, host-mediated inflammatory disease in which microbial dysbiosis and dysregulated immune responses drive the destruction of tooth-supporting tissues. Although conventional therapy remains centered on mechanical biofilm control, persistent inflammation and alveolar bone loss in susceptible individuals underscore the need for adjunctive strategies. Translating preclinical discoveries into predictable clinical outcomes, however, remains a major challenge in periodontal research. This narrative review integrates two interrelated themes, translational research methodology
Abstract by Rafael Scaf de Molon; João Paulo Steffens; Érica Dorigatti de Ávila; Wim Teughels; Thomas E. Van Dyke, Journal of Periodontal Research (2026) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1111/jre.70060