Interferons and interferon-related pathways in heart disease
Duc Tin Tran; Sri Nagarjun Batchu; Andrew Advani · 2024 · Frontiers in Cardiovascular Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Interferons (IFNs) and IFN-related pathways play key roles in the defence against microbial infection. However, these processes may also be activated during the pathogenesis of non-infectious diseases, where they may contribute to organ injury, or function in a compensatory manner. In this review, we explore the roles of IFNs and IFN-related pathways in heart disease. We consider the cardiac effects of type I IFNs and IFN-stimulated genes (ISGs); the emerging role of the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway; the seemingly paradoxical effects of the type
Abstract by Duc Tin Tran; Sri Nagarjun Batchu; Andrew Advani, Frontiers in Cardiovascular Medicine (2024) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3389/fcvm.2024.1357343