Kinin B 1 receptors contributes to acute pain following minor surgery in humans
Brahim Jaime S; Adam Albert; Wang Xiao-Min; Hamza May; Rowan Janet S; Carmona Gilberto N; Dionne Raymond A · 2010 · Molecular Pain
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Abstract
Abstract Background Kinins play an important role in regulation of pain and hyperalgesia after tissue injury and inflammation by activating two types of G-protein-coupled receptors, the kinin B 1 and B 2 receptors. It is generally accepted that the B 2 receptor is constitutively expressed, whereas the B 1 receptor is induced in response to inflammation. However, little is known about the regulatory effects of kinin receptors on the onset of acute inflammation and inflammatory pain in humans. The present study investigated the changes in gene expression of kinin receptors and the levels of thei
Abstract by Brahim Jaime S; Adam Albert; Wang Xiao-Min; Hamza May; Rowan Janet S; Carmona Gilberto N; Dionne Raymond A, Molecular Pain (2010) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1186/1744-8069-6-12