Salivary microbiome in patients with benign prostatic hyperplasia: altered composition and its association with prostate-specific antigen
Bin Zhang; Hao Guo; Zhou Li; Hao Lin; Junjie Zhi; Yifan Tang; Yifan Sun; Qiang Xia · 2025 · BMC Microbiology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Backgrounds Microbial dysbiosis in the gut and urine has been implicated in patients with benign prostatic hyperplasia (BPH) in previous studies. Additionally, emerging evidence suggests that salivary dysbiosis is associated with various diseases and oral health conditions. Building on these findings, this study aimed to investigate whether BPH patients exhibit a distinct salivary microbiome. Methods and materials We recruited a cohort of BPH patients (n = 50) and age- and BMI-matched healthy controls (HC; n = 50). Salivary samples were collected for 16S rRNA gene sequencing, and pros
Abstract by Bin Zhang; Hao Guo; Zhou Li; Hao Lin; Junjie Zhi; Yifan Tang; Yifan Sun; Qiang Xia, BMC Microbiology (2025) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1186/s12866-025-04444-z