8th IAS Conference on HIV Pathogenesis, Treatment & Prevention 19-22 July 2015, Vancouver, Canada
Pate, KM; Pohlmeyer, C; Walker-Sperling, V; Foote, J; Najarro, K; Cryer, C; Salgado, M; Gama, L · 2015 · Journal of the International AIDS Society
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Introduction Sensitive assays are needed for detection of residual HIV in patients with undetectable plasma viral loads to determine if eradication strategies are effective. The gold standard quantitative viral outgrowth assay (QVOA) underestimates the magnitude of the viral reservoir, while sensitive PCR-based assays lack the ability to distinguish replication competent from defective virus. We sought to determine whether xenograft of leukocytes from HIV-1 infected patients with undetectable plasma viral loads into severely immunocompromised mice would result in viral amplification and measur
Abstract by Pate, KM; Pohlmeyer, C; Walker-Sperling, V; Foote, J; Najarro, K; Cryer, C; Salgado, M; Gama, L, Journal of the International AIDS Society (2015) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.7448/ias.18.5.20479