Drug‐target Mendelian randomization revealed a significant association of genetically proxied metformin effects with increased prostate cancer risk
Xiaohui Sun; Jie Ping; Xingyi Guo; Jirong Long; Qiuyin Cai; Xiao‐ou Shu; Xiang Shu · 2024 · Molecular Carcinogenesis
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Abstract The association between metformin use and risk of prostate cancer remains controversial, while data from randomized trials is lacking. We aim to evaluate the association of genetically proxied metformin effects with prostate…
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Metadata source: Crossref · DOI 10.1002/mc.23692