Least Significant Change (LSC) for Serum Concentrations of 25-Hydroxyvitamin D
Pawel Pludowski; Marek Wójcik; Maciej Jaworski; Agnieszka Ochocińska; William Grant; Michael Holick · 2025 · Nutrients
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background: The least significant change (LSC) method should be introduced and considered a proper method to define the smallest clinically important difference between two consecutive measurements. Methods: The LSC was calculated based on…
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Metadata source: Crossref · DOI 10.3390/nu17132246