Benefits of Bifidobacterium breve M-16V Supplementation in Preterm Neonates - A Retrospective Cohort Study
Sanjay Patole; Shripada Rao; Anthony D. Keil; Elizabeth Nathan; Dorota A. Doherty; Karen Simmer · 2016 · PLoS ONE
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: Systematic reviews of randomised controlled trials report that probiotics reduce the risk of necrotising enterocolitis (NEC) in preterm neonates. AIM: To determine whether routine probiotic supplementation (RPS) to preterm neonates would reduce the incidence of NEC. METHODS: The incidence of NEC ≥ Stage II and all-cause mortality was compared for an equal period of 24 months 'before' (Epoch 1) and 'after' (Epoch 2) RPS with Bifidobacterium breve M-16V in neonates <34 weeks. Multivariate logistic regression analysis was conducted to adjust for relevant confounders. RESULTS: A total
Abstract by Sanjay Patole; Shripada Rao; Anthony D. Keil; Elizabeth Nathan; Dorota A. Doherty; Karen Simmer, PLoS ONE (2016) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1371/journal.pone.0150775