Longitudinal brain structural changes during clozapine treatment: associations with neuroreceptor architecture and clinical response
King B; Cannon DM; Crossley NA; Gonzalez-Valderrama A; Hallahan B; Jung WH; Kempton MJ; Kim S · 2026 · Preprint
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
In treatment-resistant schizophrenia, clozapine treatment has been associated with longitudinal reductions in subcortical volumes, ventricular enlargement, and widespread cortical thinning. However, it is unknown how these structural…
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Metadata source: Europe PMC · DOI 10.64898/2026.06.06.26354980