Statins, metformin, and RAS inhibitors did not reduce variceal bleeding risk and mortality in a large, real-life cohort of patients with cirrhosis
Nikolaus Pfisterer; Michael Schwarz; Caroline Schwarz; Florian Putre; Lukas Ritt; Florian Riedl; Lukas Hartl; Mathias Jachs · 2024 · PLOS ONE
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Previous experimental and clinical studies suggested a beneficial effect of statins, metformin, angiotensin-converting-enzyme inhibitors and angiotensin II receptor blockers (RASi) on portal hypertension. Still, their effects on…
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Metadata source: Crossref · DOI 10.1371/journal.pone.0302811