Systematic assessment of homology-based methods for fine-grained functional annotation using diverse protein families
Busi R; Machingal P; Hemachandra N; Balaji PV · 2025 · Preprint
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
The size of the protein sequence database is increasing without a consequent increase in the number of proteins with known molecular function, especially at the fine-grained level. Alignment-based approaches such as BLAST and profile…
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Metadata source: Europe PMC · DOI 10.1101/2025.09.17.676781