CXCL10 drives female-specific tau pathology progression and defines sex-dependent vulnerability in tauopathy model mice
Uenishi R; Kawata R; Manabe T; Matsuba Y; Mihira N; Takeo T; Saido TC; Hijioka M · 2026 · Preprint
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Neuroinflammation is a central driver of tauopathy, yet the precise chemokines that orchestrate the inflammatory microenvironment remain elusive. Here, we report C-X-C motif chemokine ligand 10 (CXCL10) is markedly upregulated in the…
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Metadata source: Europe PMC · DOI 10.64898/2026.04.19.719088