In-depth proteomic analysis of Varroa destructor: Detection of DWV-complex, ABPV, VdMLV and honeybee proteins in the mite
Tomáš Erban; Karel Harant; Martin Hubálek; Pavel Vítámvás; Martin Kamler; Palmiro Poltronieri; Jan Tyl; Martin Markovic · 2015 · Scientific Reports
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Abstract
We investigated pathogens in the parasitic honeybee mite Varroa destructor using nanoLC-MS/MS (TripleTOF) and 2D-E-MS/MS proteomics approaches supplemented with affinity-chromatography to concentrate trace target proteins. Peptides were detected from the currently uncharacterized Varroa destructor Macula-like virus (VdMLV), the deformed wing virus (DWV)-complex and the acute bee paralysis virus (ABPV). Peptide alignments revealed detection of complete structural DWV-complex block VP2-VP1-VP3, VDV-1 helicase and single-amino-acid substitution A/K/Q in VP1, the ABPV structural block VP1-VP4-VP2-
Abstract by Tomáš Erban; Karel Harant; Martin Hubálek; Pavel Vítámvás; Martin Kamler; Palmiro Poltronieri; Jan Tyl; Martin Markovic, Scientific Reports (2015) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1038/srep13907