490 real negative results, null findings, and replication failures in Medicine · Failed Experiment Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Wu L, Sun Q, Wang X et al. · 2026 · Plants (Basel, Switzerland)
Heavy metals in soil can be translocated to floral rewards via specific physiological pathways, potentially altering pollinator behavior and reducing plant reproductive fitness. However, the comparative effects of different heavy metals on…
View details →Sagadiev S, Hudson R Jr, Wang Y et al. · 2026 · Genetics
Integrin adhesion complexes (IACs) are a network of proteins that anchor cells to the extracellular matrix. In Caenorhabditis elegans muscle IACs exist at the bases of dense bodies and M-lines, and at the boundaries of adjacent muscle…
View details →Maeda Y, Akino S, Kondo N · 2026 · Microbes and environments
Fusarium crown and root rot (FCRR), caused by the fungus Fusarium oxysporum f. sp. asparagi, is one of the most destructive diseases affecting asparagus worldwide. Despite evidence of the suppression of FCRR by several nonpathogenic F.…
View details →Yang L, Zhuo S, Zhu X et al. · 2025 · Frontiers in endocrinology
Introduction Nonalcoholic steatohepatitis (NASH), characterized by progressive liver injury, inflammation, and fibrosis, is a leading chronic liver disease worldwide. Pharmacotherapy for NASH is thus urgently needed. Through a strategy of…
View details →El Gazar SM, El Backly RN, Lotfy WA et al. · 2026 · BMC oral health
Aim To evaluate the antimicrobial effects of Nd: YAG laser irradiation, antimicrobial photodynamic therapy (aPDT), and passive ultrasonic irrigation (PUI) in comparison with conventional irrigation with Sodium hypochlorite (NaOCl) in root…
View details →Moubayed NMS, Alsabbagh R, Smiline GAS et al. · 2025 · Natural product research
Plants contain many bioactive compounds with potent antibacterial and efflux pump inhibitory activity (EPI). In this study, gallic acid extracted from pomegranate molasses by analytical HPLC holds promise as an EPI drug for Staphylococcus…
View details →Ma H, Yan Z, Gu R et al. · 2024 · Cancer immunology, immunotherapy : CII
Background Immunotherapy, such as chimeric antigen receptor T (CAR-T) cells targeting CD33 or CD123, has been well developed over the past decade for the treatment of acute myeloid leukemia (AML). However, the inability to sustain…
View details →Liu ZL, Zhou YY, Xu QX et al. · 2025 · Insect science
The clustered regularly interspaced small palindromic repeats (CRISPR) / CRISPR-associated nuclease 9 (Cas9)-mediated gene editing technology has revolutionized the study of fundamental biological questions in various insects. Diverse…
View details →Bayram Y, Yildiz H, Ulger G et al. · 2026 · Journal of ovarian research
Background This study METHODS: A total of 662 patients treated at the Assisted Reproductive Techniques Unit of Mersin University Faculty of Medicine between 2016 and 2024 (Group 3: n=245; Group 4: n=417) were retrospectively analyzed.…
View details →Liu C, Lyu Y, Jiang Y et al. · 2023 · Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
Objective To carry out genetic analysis for a fetus with confined placental mosaicism (CPM) for trisomy 2 (T2) in conjunct with fetal uniparental disomy (UPD). Methods Amniocentesis and chromosomal karyotyping was carried out for a…
View details →Yi Zhan, Huiming Yang, Jiangtao Wang et al. · 2024 · Scientific Reports
Abstract Based on the characteristics of Kummell’s disease (KD) and related anatomical structures of the thoracolumbar spine, a novel bone cement screw system has been designed to effectively avoid the cement loosening and displacement. This experiment aimed to assess the biological effects of the novel bone cement screw system in KD on fresh cadaveric thoracolumbar spine specimens, thereby discussing its potential application value and providing a foundation for clinical implementation. This study employed a total of 50 fresh female adult cadaver specimens. Each specimen underwent extraction
View details →Kim B, Lee J, Park S et al. · 2023 · Vision research
This study investigated facial skin color differences before and after makeup. Toward this goal, a photo gauge, devised with a pair of color checkers as a reference, collected face images. In addition, color calibration and a deep-learning…
View details →Xue Z, Li X, Huang Y et al. · 2026 · BMC musculoskeletal disorders
Background Modified single-plane osteotomy is a modified technique of medial opening-wedge high tibial osteotomy (OWHTO). This study aimed to investigate the effects of tourniquet use versus non-use during modified single-plane high tibial…
View details →Park EC, Harris LM, Sigel AN et al. · 2023 · Behaviour research and therapy
Existing evidence suggests a link between physical pain and suicide, but the nature of this relationship remains unknown. To address this critical gap in knowledge, the present study leveraged a validated virtual reality (VR) suicide…
View details →Wollina U, Schönlebe J · 2023 · Acta dermatovenerologica Croatica : ADC
Dear Editor, Silicone is a hydrophobic polymer containing silicon. Silicon is an essential compound of soft tissue proteoglycans. Reports about morphea and other autoimmune connective tissue disorders in association with silicone implants…
View details →McKyton A, Marks Ohana D, Nahmany E et al. · 2023 · Current biology : CB
How will people who spent their visual lives with only rods respond to cone function restoration? Will they be able suddenly see the colors of the rainbow? CNGA3-achromatopsia is a congenital hereditary disease in which cone dysfunction…
View details →Hinkelmann MA, Schibler D, Frei F et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
INTRODUCTION: Midshaft clavicle fractures are commonly treated with plate fixation; however, the selected plate working length varies widely. Biomechanical principles suggest potential effects on fracture healing, but clinical evidence…
View details →López-Sagaseta J, Urdiciain A · 2025 · Scientific reports
Artificial intelligence (AI) and deep learning are making groundbreaking strides in protein structure prediction. AlphaFold is remarkable in this arena for its outstanding accuracy in modelling proteins fold based solely on their amino…
View details →Han S, Long NM · 2025 · Imaging neuroscience (Cambridge, Mass.)
Engagement of the retrieval state (or mode) is theorized to be a precursor to successful retrieval, but precisely when the retrieval state is engaged is unclear. Our aim in the present study is to determine the time course of retrieval…
View details →Tamasauskiene L, Gradauskiene B · 2024 · Journal of inflammation (London, England)
Background T lymphocyte helper (Th) 2 plays the main role in pathogenesis of allergic airway diseases (AAD). Recent studies showed that interleukin (IL) 33, Th17 and Th22 also may be involved in allergic inflammation. The aim is to…
View details →Petersen Dias A, Orsel K, Gammariello CS et al. · 2025 · Research in Veterinary Science
Digital dermatitis (DD) is a polymicrobial, multifactorial hoof disorder with an undefined etiology, and existing animal models fail to induce a fast, standardized infection in bovine skin. This study explored bacterial inoculation methods…
View details →Bender O, Shemesh OA, Bar DZ · 2026 · Journal of Alzheimer's disease : JAD
The etiology of Alzheimer's disease (AD) remains a subject of intense investigation. While the 2024 Lancet Commission report attributes approximately 45% of global dementia cases to 14 modifiable risk factors, it notably excludes…
View details →Chen P, Zhao W, Li Y et al. · 2025 · BMC pregnancy and childbirth
OBJECTIVE: Thyroid hormones are essential for normal pregnancy and fetal development. The relationship between thyroid disease and the risk of spontaneous abortion (SA) and recurrent spontaneous abortion (RSA) has been reported, but…
View details →Stepanova EV, Strube MJ, Mazur KD · 2023 · The Journal of social psychology
In two studies, participants completed an implicit attractiveness task with faces as primes varying on (a) facial features from Afrocentric to Eurocentric and (b) skin tone from dark to light, and target pictures of environmental scenes…
View details →Omidifar N, Najafi E, Nasiri K et al. · 2025 · BMC pregnancy and childbirth
BACKGROUND: Despite numerous studies on the impact of stress on post-in vitro fertilization (IVF) clinical outcomes are contradictory and researchers recommend the need for further studies. Therefore, the purpose of the present study was…
View details →da Eira Silva V, Abele M, Bercovitz I et al. · 2025 · Workplace health & safety
Background The use of the N95 respirator outside work environments calls for a deeper understanding of the factors that interfere with its fitting, thus effectiveness. Here we determined how beard length influences N95 effectiveness. This…
View details →Shook NJ, Oosterhoff B · 2020 · Politics and the life sciences : the journal of the Association for Politics and the Life Sciences
Disgust has been consistently associated with greater political conservatism. Two explanations have been proposed for this link. According to a pathogen threat model, disgust serves a pathogen-avoidance function, encouraging more…
View details →Johnson B, Addolorato G, Lesch O et al. · 2023 · Frontiers in psychiatry
A core principle in the pursuit of scientific knowledge is that science is self-correcting and that important results should be replicable. Hypotheses need to be reinforced, adjusted, or rejected when novel results are obtained.…
View details →Sekmen S, Hursoy N, Panc K et al. · 2026 · Clinical imaging
Aim This study aims to explore the correlation between background parenchymal enhancement (BPE) observed in breast magnetic resonance imaging (MRI) and the presence of breast cancer. Materials and methods A total of 761 patients (326…
View details →Omole-ohonsi A, Ashimi AO · 2008 · Ibom Medical Journal
Objective: To evaluate the feasibility and outcome of caesarean myomectomy. Patients and Methods: A retrospective study of cases of caesarean myomectomy at the Aminu Kano Teaching Hospital, Kano, Nigeria, a tertiary health facility in a developing country between January 1998 and December 2004. Outcome Measures: Age and parity of the women, number, size and location of fibroids, duration of operation, estimated blood loss, postoperative complications and duration of hospital stay. Results: Sixteen cases of caesarean myomectomy were done during the study period using the tourniquet method. It i
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