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490 real negative results, null findings, and replication failures in Medicine · Failed Experiment Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Failed Experiment ReportMedicine

Dentin Bond Strength of Resin Cements Under Simulated Intraoral Humidity Conditions.

Washino T, Nikaido T, Burrow MF et al. · 2026 · Dental traumatology : official publication of International Association for Dental Traumatology

Background/aims Adhesive procedures performed after dental trauma are often carried out in emergency settings with compromised isolation due to bleeding, limited access, and patient cooperation. This study evaluated how variation in…

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Failed Experiment ReportOpen accessMedicine

Dried Black Soldier Fly (<i>Hermetia illucens</i>) Larvae in a Sustainable Diet for Laying Hens: Effects on Welfare and Behavior.

Znazen Y, Gaddes M, Janssens GPJ et al. · 2026 · Animals : an open access journal from MDPI

This study evaluated the effects of locally sourced ingredient dietary, with or without supplementation of black soldier fly ( Hermetia illucens ; BSF) larvae, on laying hen welfare. A total of 150 Lohman White hens aged 30 weeks were…

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Failed Experiment ReportMedicine

Exploratory Machine Learning-Based Classification of Type 2 Diabetes Using Routine Clinical Parameters: A Single-Center Comparative Study.

Bülbül N, Çiftçi R, Atik İ et al. · 2026 · Healthcare (Basel, Switzerland)

Background/Objectives: Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disorder associated with substantial long-term morbidity and mortality. Routinely collected anthropometric, biochemical, and hematological variables may…

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Failed Experiment ReportMedicine

Survival Outcomes in Early Onset Appendiceal Adenocarcinoma (EOAA).

Gujarathi, Belmont, Rodman et al. · 2026 · Annals of surgical oncology

The incidence of early onset (age&#x2009;<&#x2009;50 years at diagnosis) appendiceal adenocarcinoma (EOAA) is rising alarmingly. Reported data on etiology, treatment, and outcomes is scarce. In this study, we report clinical outcomes for…

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Failed Experiment ReportMedicine

Age-dependent alterations in anterior cingulate excitation-inhibition balance in major depressive disorder revealed by 7-Tesla magnetic resonance spectroscopy.

Yoshihara, Suwa, Kubota et al. · 2026 · NeuroImage. Clinical

Altered excitation-inhibition (E/I) balance has been implicated in the pathophysiology of major depressive disorder (MDD), but previous magnetic resonance spectroscopy (MRS) findings have been inconsistent, partly due to methodological…

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Failed Experiment ReportMedicine

Evaluation of Neonatal Sprague-Dawley Rats as a Potential Animal Model for the Neurovirulence Test of an Iranian Mumps Vaccine Strain, RS-12.

Mohammad Kazem, Mohammad, Mohammad Hasan et al. · 2025 · Archives of Razi Institute

Mumps virus (MuV), a neurotropic member of paramyxoviridae, causes mumps disease. Since the 1960s, when the first live-attenuated vaccine against the MuV was developed, mumps outbreaks have dramatically decreased. A monkey-based…

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Failed Experiment ReportMedicine

Antiviral Prophylaxis for Delayed Facial Nerve Palsy Following Vestibular Schwannoma Resection: Single Institutional Series With Systematic Literature Review and Meta-Analyses of 7136 Patients.

Blue, Alvarez, Hines et al. · 2026 · Neurosurgery

Delayed facial nerve palsy (DFNP) is a recognized complication of vestibular schwannoma resection, with proposed mechanisms including viral reactivation, inflammation, and ischemia. Elevated herpes simplex virus and varicella zoster virus…

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Failed Experiment ReportMedicine

Transcranial Direct Current Stimulation Combined with Neurofunctional Motor Training in Autistic Children: A Randomized, Sham-Controlled, Double-Blind Clinical Trial.

Araujo, Araujo, Silva et al. · 2026 · Journal of motor behavior

The study investigated the effects of ten 20-minute sessions of neurofunctional motor training combined with anodal transcranial direct current stimulation (tDCS) over the primary motor cortex or cerebellum on motor skills in autistic…

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Failed Experiment ReportMedicine

Effect of injectable platelet-rich fibrin on orthodontically induced apical root resorption following non-extraction-based orthodontic treatment in adults: A randomized controlled clinical trial.

Idris, Burhan, Hajeer et al. · 2026 · The Journal of international medical research

ObjectiveTo investigate the effect of repeated submucosal administration of injectable platelet-rich fibrin in the buccal region of the lower incisors on orthodontically induced apical root resorption in patients with moderate…

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Failed Experiment ReportMedicine

Efficacy and safety of belapectin for the prevention of esophageal varices in patients with MASH cirrhosis: The randomized, placebo-controlled NAVIGATE trial.

Chalasani, Vuppalanchi, Noureddin et al. · 2026 · Hepatology (Baltimore, Md.)

Belapectin reduced variceal development in a subgroup of patients with MASH cirrhosis. We report the efficacy and safety of belapectin in patients with MASH cirrhosis and portal hypertension without varices at baseline. NAVIGATE was a…

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Failed Experiment ReportMedicine

Early onset radiation-induced leukoencephalopathy in patients treated for a glioblastoma by STUPP protocol and risk factors evaluation, an ancillary study of the phase III ASTER protocol.

Balcerac, Cuzzubbo, Bompaire et al. · 2026 · Revue neurologique

Since 2005, the standard treatment for newly diagnosed glioblastoma involves radiotherapy combined with concomitant and adjuvant temozolomide (TMZ), as per the Stupp protocol. A known long-term complication of radiotherapy is…

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Failed Experiment ReportOpen accessMedicine

Is biceps augmentation effective for scope-assisted lower trapezius tendon transfer in posterosuperior irreparable rotator cuff tears? A retrospective short-term clinical comparison.

Baek CH, Elhassan BT, Lim C et al. · 2026 · Archives of orthopaedic and trauma surgery

Introduction Although favorable clinical outcomes of scope-assisted lower trapezius tendon transfer (SALTT) have been reported in posterosuperior irreparable rotator cuff tears (PSIRCTs) patients, the limited restoring of static stability…

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Failed Experiment ReportOpen accessMedicine

EVALUATION OF FLEXURAL STRENGTH OF DIFFERENT RESTORATIVE MATERIALS

Almira Ada Diken Türksayar, Simge Baytur · 2023 · Sabiad

Objective: The aim of this in vitro study was to compare the biaxial flexural strengths of permanent restorative materials produced by additive manufacturing and milling after thermal aging. Material and methods: For this study, three study groups were formed by producing disc-shaped specimens with a 3D printer (Form3, Formlabs) using permanent crown material (Permanent Crown, Somerville, MA) and two different resin-containing materials (Brilliant Crios,Coltene/ Whaledent; Cerasmart, GC Europe) by the milling method (n=10). The entire production process was carried out in accordance with the m

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Failed Experiment ReportOpen accessMedicine

Results of the performance test for quality assessment of personal radiation dosimetry services including the influence of the dosimeter readout frequency

Chen-Ju Feng, Chin-Hui Wu, Yi-Hui Huang et al. · 2022 · Scientific Reports

Abstract This study was to determine the significance of factors considered for the measurement accuracy of personal dosimeter in dosimetry services such as dosimetry service, irradiation category, years of use and readout frequency. The investigation included management information questionnaire, on-site visit and blind test. The blind test with random selected personal badge was used in inter-comparison of eight dosimetry services, and the test results followed ANSI/HPS N13.11 criteria. This study also analyzed the measurement deviations if they felt in the criteria of ICRP 75 or not. One-wa

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Failed Experiment ReportOpen accessMedicine

Effects of co-occurrence and intra- and interspecific interactions between Drosophila suzukii and Zaprionus indianus

Larine de Paiva Mendonça, Khalid Haddi, Wesley Augusto Conde Godoy · 2023 · PLoS ONE

In drosophilids, competition and coexistence can impact survivorship, growth, and reproductive output. Here, we evaluated direct competition between two co-occurring fruit flies, the spotted-wing drosophila Drosophila suzukii and the African fig fly Zaprionus indianus, comparing results from field collections with laboratory experiments. Field collections were conducted to evaluate co-occurrence between species. In the laboratory, different densities of eggs of each species were provided an artificial diet, and intra- and interspecific densities were evaluated regarding biological traits such

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